CAJ | 학술논문

目的：了解新生儿高胆红素血症T O RC H病毒感染的情况，探讨两者之间的相关性。方法选择2014年1～12月该院住院的644例高胆红素血症新生儿（新生儿高胆红素血症组），另选择同期住院的160例健康新生儿作为对照组，采用化学发光法和ELISA法进行血清TORCH‐IgM抗体测定，观察两组感染的情况。结果644例新生儿高胆红素血症组中TORCH‐IgM抗体阳性58例，阳性率为9．0％，对照组160例中T O RC H‐Ig M抗体阳性0例，阳性率为0％，两组比较差异有统计学意义（ P＜0．05）。其中微小病毒B19感染率最高，阳性率为7．3％，CMV‐IgM 抗体阳性率为1．7％。结论 TORCH感染与新生儿高胆红素血症相关，是其重要原因之一，应在高胆红素血症新生儿中进行TORCH项目的实验室检查。
목적：료해신생인고담홍소혈증T O RC H병독감염적정황，탐토량자지간적상관성。방법선택2014년1～12월해원주원적644례고담홍소혈증신생인（신생인고담홍소혈증조），령선택동기주원적160례건강신생인작위대조조，채용화학발광법화ELISA법진행혈청TORCH‐IgM항체측정，관찰량조감염적정황。결과644례신생인고담홍소혈증조중TORCH‐IgM항체양성58례，양성솔위9．0％，대조조160례중T O RC H‐Ig M항체양성0례，양성솔위0％，량조비교차이유통계학의의（ P＜0．05）。기중미소병독B19감염솔최고，양성솔위7．3％，CMV‐IgM 항체양성솔위1．7％。결론 TORCH감염여신생인고담홍소혈증상관，시기중요원인지일，응재고담홍소혈증신생인중진행TORCH항목적실험실검사。
Objective To investigate TORCH infections in neonatal hyperbilirubinemia ,and explore the relationship between them.Methods 644casesofneonatalhyperbilirubinemiainourhospitalfromJanuarytoDecemberin2014werechosenasneonatal hyperbilirubinemia group ,160 cases of healthy newborns in the same period were selected as control group .Chemiluminescence im‐munoassay and Enzyme‐linked immune‐sorbent assay (ELISA )were used to detect the TORCH‐IgM antibody .TORCH infections wereobservedbetweenthetwogroups.Results 58casesofpositiveTORCH‐IgMantibodywerefoundin644casesofneonatalhy‐perbilirubinemia group ,detection rate of TORCH‐IgM antibody was 9 .0% ,0 case of positive TORCH‐IgM antibody was found in 160 cases of the control group ,detection rate of TORCH‐IgM antibody was 0 .0% ,the difference was statistically significant be‐tween the two groups(P<0 .05) .The infection rate of B19 was the highest ,the positive rates of B19 ,CMV were 7 .3% ,1 .7% .Con‐clusion There would be a possible relation between TORCH infections and neonatal hyperbilirubinemia ,TORCH infection is one of the causes of neonatal hyperbilirubinemia ,and the screening of TORCH in neonatal hyperbilirubinemia is necessary .