中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2015年
21期
124-125
,共2页
小剂量多巴胺%心功能III-IV级%呋塞米
小劑量多巴胺%心功能III-IV級%呋塞米
소제량다파알%심공능III-IV급%부새미
A small dose of dopamine%Cardiac functional class III-IV%Furosemide
目的：探究早期应用小剂量多巴胺联合呋塞米治疗心功能III-IV级心力衰竭的疗效。方法整群选自2012年8月-2014年12月长春市第二医院心内科就诊的84例心功能III-IV级心力衰竭的患者，随机分为两组，治疗组42例早期给予静脉持续泵入小剂量多巴胺（0.5-1.0ug.kg-1.min-1）联合呋塞米（20-40mg/d）静脉注射治疗，对照组42例仅静脉注射呋塞米（20-40mg/d）。比较两组治疗效果、左室射血分数（LVEF）、左室舒张末内径（LVIDd）和B型利钠肽（BNP）水平。结果治疗组总有效率90.48%（38/42），对照组总有效率73.81%（31/42），两组比较差异有统计学意义（χ2=3.153，P=0.0012）。治疗后两组LVEF、LVIDd、BNP水平均有改善，治疗组改善优于对照组，差异有统计学意义，P<0.05。结论早期应用小剂量多巴胺联合呋塞米可改善心功能III-IV级心力衰竭患者的心功能，提高治疗效果。
目的：探究早期應用小劑量多巴胺聯閤呋塞米治療心功能III-IV級心力衰竭的療效。方法整群選自2012年8月-2014年12月長春市第二醫院心內科就診的84例心功能III-IV級心力衰竭的患者，隨機分為兩組，治療組42例早期給予靜脈持續泵入小劑量多巴胺（0.5-1.0ug.kg-1.min-1）聯閤呋塞米（20-40mg/d）靜脈註射治療，對照組42例僅靜脈註射呋塞米（20-40mg/d）。比較兩組治療效果、左室射血分數（LVEF）、左室舒張末內徑（LVIDd）和B型利鈉肽（BNP）水平。結果治療組總有效率90.48%（38/42），對照組總有效率73.81%（31/42），兩組比較差異有統計學意義（χ2=3.153，P=0.0012）。治療後兩組LVEF、LVIDd、BNP水平均有改善，治療組改善優于對照組，差異有統計學意義，P<0.05。結論早期應用小劑量多巴胺聯閤呋塞米可改善心功能III-IV級心力衰竭患者的心功能，提高治療效果。
목적：탐구조기응용소제량다파알연합부새미치료심공능III-IV급심력쇠갈적료효。방법정군선자2012년8월-2014년12월장춘시제이의원심내과취진적84례심공능III-IV급심력쇠갈적환자，수궤분위량조，치료조42례조기급여정맥지속빙입소제량다파알（0.5-1.0ug.kg-1.min-1）연합부새미（20-40mg/d）정맥주사치료，대조조42례부정맥주사부새미（20-40mg/d）。비교량조치료효과、좌실사혈분수（LVEF）、좌실서장말내경（LVIDd）화B형리납태（BNP）수평。결과치료조총유효솔90.48%（38/42），대조조총유효솔73.81%（31/42），량조비교차이유통계학의의（χ2=3.153，P=0.0012）。치료후량조LVEF、LVIDd、BNP수평균유개선，치료조개선우우대조조，차이유통계학의의，P<0.05。결론조기응용소제량다파알연합부새미가개선심공능III-IV급심력쇠갈환자적심공능，제고치료효과。
Objective Curative effect observation on early application in treatment to functional class III-IV heart failure with small dose of dopamine combined with furosemide. Methods 84 patients, with cardiac functional class III-IV heart failure, accept-ed by the Department of Cardiology, Changchun Second Hospital, from August 2012 to December 2014, were selected and ran-domly divided into two groups, the treatment group, 42 cases, early made intravenous continuous infusion of small dose dopamine (0.5-1.0 ug·kg-1·min-1) combined with furosemide (20-40mg/d) intravenous injection therapy, while control group, 42 cases, only made intravenous injection of furosemide (20-40mg/d). Therapeutic effects, left ventricular ejection fraction (LVEF), left ven-tricular internal diameter at end-diastole (LVIDd) and B-type natriuretic peptide (BNP) levels were compared. Results The total effective rate of treatment group was 90.48% (38/42), and the total efficiency of control group 73.81% (31/42), so the difference was statistically significant (X2=3.153, P=0.0012). LVEF, LVIDd, and BNP levels of the two groups were improved after treatment, and the treatment group's improvement was better than that of the control group, with statistical significance, P<0.05. Conclusion Early application of small dose dopamine combined with furosemide, patients with cardiac functional class III-IV heart failure, car-diac function and therapeutic effect could be improved.
