蚌埠医学院学报
蚌埠醫學院學報
방부의학원학보
ACTA ACADEMIAE MEDICINAE BENGBU
2015年
7期
899-900,901
,共3页
糖尿病%胰岛素泵%强化治疗
糖尿病%胰島素泵%彊化治療
당뇨병%이도소빙%강화치료
diabetes mellitus%insulin pump%intensive treatment
目的::观察胰岛素泵在2型糖尿病强化治疗中的疗效和安全性。方法:将40例2型糖尿病患者随机分为对照组和治疗组各20例。对照组予诺和灵R三餐前+甘精胰岛素睡前皮下注射,治疗组予胰岛素泵连续皮下注射超短效赖脯胰岛素。记录2组患者治疗前后空腹、餐后2h血糖值,血糖达标时间、胰岛素用量及低血糖发生率。结果:2组空腹血糖值、餐后2h血糖值均较治疗前明显下降(P<0.01),但2组血糖结果差异均无统计学意义(P>0.05)。2组胰岛素用量差异有统计学意义(P<0.01),2组低血糖发生率差异无统计学意义(P>0.05)。结论:胰岛素泵连续皮下注射较符合生理需求,血糖控制佳,低血糖发生率低,是值得推广的糖尿病治疗方法。
目的::觀察胰島素泵在2型糖尿病彊化治療中的療效和安全性。方法:將40例2型糖尿病患者隨機分為對照組和治療組各20例。對照組予諾和靈R三餐前+甘精胰島素睡前皮下註射,治療組予胰島素泵連續皮下註射超短效賴脯胰島素。記錄2組患者治療前後空腹、餐後2h血糖值,血糖達標時間、胰島素用量及低血糖髮生率。結果:2組空腹血糖值、餐後2h血糖值均較治療前明顯下降(P<0.01),但2組血糖結果差異均無統計學意義(P>0.05)。2組胰島素用量差異有統計學意義(P<0.01),2組低血糖髮生率差異無統計學意義(P>0.05)。結論:胰島素泵連續皮下註射較符閤生理需求,血糖控製佳,低血糖髮生率低,是值得推廣的糖尿病治療方法。
목적::관찰이도소빙재2형당뇨병강화치료중적료효화안전성。방법:장40례2형당뇨병환자수궤분위대조조화치료조각20례。대조조여낙화령R삼찬전+감정이도소수전피하주사,치료조여이도소빙련속피하주사초단효뢰포이도소。기록2조환자치료전후공복、찬후2h혈당치,혈당체표시간、이도소용량급저혈당발생솔。결과:2조공복혈당치、찬후2h혈당치균교치료전명현하강(P<0.01),단2조혈당결과차이균무통계학의의(P>0.05)。2조이도소용량차이유통계학의의(P<0.01),2조저혈당발생솔차이무통계학의의(P>0.05)。결론:이도소빙련속피하주사교부합생리수구,혈당공제가,저혈당발생솔저,시치득추엄적당뇨병치료방법。
Objective:To observe the curative effect and safety of insulin pump in intensive treatment of type 2 diabetes mellitus. Methods:Forty patients with type 2 diabetes mellitus were randomized to control group and treatment group. The control group were injected Novolin R before meals and insulin glargine at bedtime,while the treatment group received continuous subcutaneous insulin infusion with ultra-short-acting insulin lispro. The fasting blood glucose level,2-hour postprandial blood glucose,the time when blood glucose reached the standard,the dosage of insulin and the incidence of hypoglycemia of the patients in each group were respectively recorded before and after treatment. Results:The fasting blood glucose level and 2-hour postprandial blood glucose in both groups decreased obviously(P<0. 01). The contrast differences between the results of the two groups were not statistically significant(P>0.05).The contrast differences in the dosage of insulin were statistically significant(P <0. 01). The contrast differences in the incidence of hypoglycemia were not statistically significant(P>0. 05). Conclusions:Insulin pump continuous infusion is consistent with the physiological situation and good for controlling the blood glucose and lowering the incidence of hypoglycemia. This therapy is worth popularizing for treatment of diabetes mellitus.