中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2015年
8期
484-487
,共4页
曾孝宇%黄悦%王桂琴%赵少贞
曾孝宇%黃悅%王桂琴%趙少貞
증효우%황열%왕계금%조소정
角膜磨镶术,激光原位%近视,退行性%治疗结果
角膜磨鑲術,激光原位%近視,退行性%治療結果
각막마양술,격광원위%근시,퇴행성%치료결과
Keratomileusis,laser in situ%Myopia,degenerative%Therapy outcome
目的 评价准分子激光原位角膜磨镶术(LASIK)治疗高度及超高度近视术后10年的安全性和有效性.方法 回顾性系列病例研究.2002年10月至2004年5月在我院行LASIK手术治疗且于近期来院复诊的41例高度近视患者(80眼)纳入研究,按等效球镜度(SE)分为2组:A组:SE-6.00～-10.00 D,44眼;B组:SE≥-10.25 D,36眼.检查裸眼视力(UCVA)、SE和最佳矫正视力(BCVA),分析术后屈光回退量、UCVA≥4.7或≥5.0所占的比例.对数据进行t检验、卡方检验、Pearson相关性分析.结果 80眼术后10年UCVA≥4.7为85％,≥5.0为45％,2组BCVA无丢失2行及2行以上者.A组UCVA≥5.0所占的比例高于B组,差异有统计学意义(x2--5.518,P＜0.05).术后10年SE为0.00～-8.50 D,平均(-0.91±1.43)D,与术前比较差异有统计学意义(t=-28.196,P＜0.01).A组屈光度回退量≤0.50 D者所占比例高于B组,差异有统计学意义(x2=6.865,P＜0.05).术后10年屈光回退量≥1.00 D共30眼,平均(2.42±1.63)D.该30眼术后屈光回退量与实际角膜厚度-预留角膜厚度的差值呈正相关(r=0.706,P＜0.01).结论 LASIK治疗高度近视患者远期疗效肯定,安全性好,但对度数较高患者预测性相对较低.
目的 評價準分子激光原位角膜磨鑲術(LASIK)治療高度及超高度近視術後10年的安全性和有效性.方法 迴顧性繫列病例研究.2002年10月至2004年5月在我院行LASIK手術治療且于近期來院複診的41例高度近視患者(80眼)納入研究,按等效毬鏡度(SE)分為2組:A組:SE-6.00～-10.00 D,44眼;B組:SE≥-10.25 D,36眼.檢查裸眼視力(UCVA)、SE和最佳矯正視力(BCVA),分析術後屈光迴退量、UCVA≥4.7或≥5.0所佔的比例.對數據進行t檢驗、卡方檢驗、Pearson相關性分析.結果 80眼術後10年UCVA≥4.7為85％,≥5.0為45％,2組BCVA無丟失2行及2行以上者.A組UCVA≥5.0所佔的比例高于B組,差異有統計學意義(x2--5.518,P＜0.05).術後10年SE為0.00～-8.50 D,平均(-0.91±1.43)D,與術前比較差異有統計學意義(t=-28.196,P＜0.01).A組屈光度迴退量≤0.50 D者所佔比例高于B組,差異有統計學意義(x2=6.865,P＜0.05).術後10年屈光迴退量≥1.00 D共30眼,平均(2.42±1.63)D.該30眼術後屈光迴退量與實際角膜厚度-預留角膜厚度的差值呈正相關(r=0.706,P＜0.01).結論 LASIK治療高度近視患者遠期療效肯定,安全性好,但對度數較高患者預測性相對較低.
목적 평개준분자격광원위각막마양술(LASIK)치료고도급초고도근시술후10년적안전성화유효성.방법 회고성계렬병례연구.2002년10월지2004년5월재아원행LASIK수술치료차우근기래원복진적41례고도근시환자(80안)납입연구,안등효구경도(SE)분위2조:A조:SE-6.00～-10.00 D,44안;B조:SE≥-10.25 D,36안.검사라안시력(UCVA)、SE화최가교정시력(BCVA),분석술후굴광회퇴량、UCVA≥4.7혹≥5.0소점적비례.대수거진행t검험、잡방검험、Pearson상관성분석.결과 80안술후10년UCVA≥4.7위85％,≥5.0위45％,2조BCVA무주실2행급2행이상자.A조UCVA≥5.0소점적비례고우B조,차이유통계학의의(x2--5.518,P＜0.05).술후10년SE위0.00～-8.50 D,평균(-0.91±1.43)D,여술전비교차이유통계학의의(t=-28.196,P＜0.01).A조굴광도회퇴량≤0.50 D자소점비례고우B조,차이유통계학의의(x2=6.865,P＜0.05).술후10년굴광회퇴량≥1.00 D공30안,평균(2.42±1.63)D.해30안술후굴광회퇴량여실제각막후도-예류각막후도적차치정정상관(r=0.706,P＜0.01).결론 LASIK치료고도근시환자원기료효긍정,안전성호,단대도수교고환자예측성상대교저.
Objective To evaluate the safety and efficacy of laser in situ keratomileusis (LASIK)for high and ultra-high myopia 10 years after surgery.Methods In this retrospective study,41 patients (80 eyes) who underwent LASIK from October 2002 to May 2004 for myopia were recently reexamined.Data for uncorrected visual acuity (UCVA),refractive error,and best corrected visual acuity (BCVA)were evaluated as well as the degree of regression,the percentage of UCVA≥5.0,and loss of ≥2 lines of BCVA.Patients were divided into two groups based on average preoperative spherical equivalent:group A:-6.00～-10.00 D (44 eyes) and group B:＞10.25 D (36 eyes).A t test was used for normally distributed data.Attributes data were analyzed using a x2 test.A Pearson correlation coefficient was used for correlation analysis.Results A UCVA of ≥4.7 was achieved in 85％ of the patients and ≥5.0 in 45％ among the 80 eyes.No patients lost ≥2 lines of BCVA.The percentage of UCVA ≥1.0 in group A was significantly higher than that in group B (x2=5.518,P＜0.05).The mean spherical equivalent was-0.91±1.43 D 10 years after LASIK surgery,which differed significantly from the preoperative data of-10.10±2.42 D (t=-28.196,P＜0.01).The percentage of regression ≤0.50 D was higher in group A than group B (x2=6.865,P＜0.05).A regression ≥1.00 D was obtained in 30 eyes after 10 years.A positive correlation was found in these 30 eyes between the degree of regression and the difference between the actual and expected corneal thickness (r=0.706,P＜0.01).Conclusion LASIK for high myopia is an effective and safe long-term procedure,but it is slightly less predictive in patients with ultra-high myopia.
