中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2015年
16期
2512-2514
,共3页
降钙素原%C 反应蛋白质%社区获得性肺炎
降鈣素原%C 反應蛋白質%社區穫得性肺炎
강개소원%C 반응단백질%사구획득성폐염
Procalcitonin%C -reaction protein%Community acquired pneumonia
目的：探讨血清降钙素原（PCT）在社区获得性肺炎诊治中的临床意义。方法收集住院的社区获得性肺炎患者42例作为观察组，根据患者病情转归情况分为好转组及加重组，另选取同期来院就诊的急性上呼吸道感染患者30例作为对照组，分别于第1天、第3天、第7天检测血清 PCT、CRP，对结果进行对比分析。结果观察组第1天、第3天、第7天 PCT 分别为（1．18±0．32）μg／L、（0．78±0．12）μg／L、（0．18±0．04）μg／L，CRP 分别为（154．15±21．58）mg／L、（67．42±20．35）mg／L、（15．43±7．76）mg／L，对照组第1天、第3天、第7天 PCT 分别为（0．05±0．01）μg／L、（0．04±0．02）μg／L、（0．05±0．02）μg／L，CRP 分别为（9．39±2．22）mg／L、（8．83±2．91）mg／L、（7．06±3．03）mg／L，两组差异均有统计学意义（t ＝6．15、10．85、4．86，58．69、16．79、11．99，均 P ＜0．05）；加重组第1天、第3天、第7天 PCT 水平均显著高于好转组，差异均有统计学意义（t ＝17．86、18．21、20．65，均 P ＜0．05）。结论PCT 作为社区获得性肺炎的诊治监测指标，与 CRP 结果相比敏感性更高、特异性更强，将有助于临床医生早期诊断并确定合理的抗菌素治疗方案。
目的：探討血清降鈣素原（PCT）在社區穫得性肺炎診治中的臨床意義。方法收集住院的社區穫得性肺炎患者42例作為觀察組，根據患者病情轉歸情況分為好轉組及加重組，另選取同期來院就診的急性上呼吸道感染患者30例作為對照組，分彆于第1天、第3天、第7天檢測血清 PCT、CRP，對結果進行對比分析。結果觀察組第1天、第3天、第7天 PCT 分彆為（1．18±0．32）μg／L、（0．78±0．12）μg／L、（0．18±0．04）μg／L，CRP 分彆為（154．15±21．58）mg／L、（67．42±20．35）mg／L、（15．43±7．76）mg／L，對照組第1天、第3天、第7天 PCT 分彆為（0．05±0．01）μg／L、（0．04±0．02）μg／L、（0．05±0．02）μg／L，CRP 分彆為（9．39±2．22）mg／L、（8．83±2．91）mg／L、（7．06±3．03）mg／L，兩組差異均有統計學意義（t ＝6．15、10．85、4．86，58．69、16．79、11．99，均 P ＜0．05）；加重組第1天、第3天、第7天 PCT 水平均顯著高于好轉組，差異均有統計學意義（t ＝17．86、18．21、20．65，均 P ＜0．05）。結論PCT 作為社區穫得性肺炎的診治鑑測指標，與 CRP 結果相比敏感性更高、特異性更彊，將有助于臨床醫生早期診斷併確定閤理的抗菌素治療方案。
목적：탐토혈청강개소원（PCT）재사구획득성폐염진치중적림상의의。방법수집주원적사구획득성폐염환자42례작위관찰조，근거환자병정전귀정황분위호전조급가중조，령선취동기래원취진적급성상호흡도감염환자30례작위대조조，분별우제1천、제3천、제7천검측혈청 PCT、CRP，대결과진행대비분석。결과관찰조제1천、제3천、제7천 PCT 분별위（1．18±0．32）μg／L、（0．78±0．12）μg／L、（0．18±0．04）μg／L，CRP 분별위（154．15±21．58）mg／L、（67．42±20．35）mg／L、（15．43±7．76）mg／L，대조조제1천、제3천、제7천 PCT 분별위（0．05±0．01）μg／L、（0．04±0．02）μg／L、（0．05±0．02）μg／L，CRP 분별위（9．39±2．22）mg／L、（8．83±2．91）mg／L、（7．06±3．03）mg／L，량조차이균유통계학의의（t ＝6．15、10．85、4．86，58．69、16．79、11．99，균 P ＜0．05）；가중조제1천、제3천、제7천 PCT 수평균현저고우호전조，차이균유통계학의의（t ＝17．86、18．21、20．65，균 P ＜0．05）。결론PCT 작위사구획득성폐염적진치감측지표，여 CRP 결과상비민감성경고、특이성경강，장유조우림상의생조기진단병학정합리적항균소치료방안。
Objective To investigate the clinical significance of serum level of the diagnosis and treatment of community acquired pneumonia.Methods 42 hospital patients with pneumonia obtained from community were slect-ed as the observation group.According to patient outcome,they were divided into improvement group and aggravated group.Another selection during the same period in hospital for treatment of acute upper respiratory tract infection in patients with 30 cases was the control group.Respectively,in the 1 day,3 days,7 days the results of serum calcitonin angiotensinogen (PCT)and CRP were compared and analyzed.Results In observation group,PCT of first day,third days and seventh days were respectively (1.18 ±0.32)μg/L,(0.78 ±0.12)μg/L and (0.18 ±0.04)μg/L;CRP were respectively (154.15 ±21.58)mg/L,(67.42 ±20.35)mg/L and (15.43 ±7.76)mg/L.In the control group, PCT of first days,third days and seventh days were respectively (0.05 ±0.01 )μg/L,(0.04 ±0.02)μg/L and (0.05 ±0.02)μg/L,while CRP were respectively (9.39 ±2.22)mg/L,(8.83 ±2.91 )mg/L and (7.06 ± 3.03)mg/L.There were significant differences between the two groups (t =6.15,10.85,4.86,58.69,16.79,11.99,all P <0.05).In the aggravated group,PCT levels of first days,third days and seventh days were significantly higher than that of the improved group,the differences were statistically significant (t =17.86,18.21,20.65,all P <0.05). Conclusion As a monitoring marker,PCT showed higher sensibility and specificity than CRP in diagnosis and treat-ment of CAP,and it would be helpful to make early diagnosis and certain the therapeutic schedule to use antibiotics.
