中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2015年
16期
2491-2493,2494
,共4页
肺疾病,慢性阻塞性%体层摄影术,X 线计算机
肺疾病,慢性阻塞性%體層攝影術,X 線計算機
폐질병,만성조새성%체층섭영술,X 선계산궤
Pulmonary disease,Chronic obstruction%Tomography,X -ray computer
目的:探讨不同慢性阻塞性肺疾病(COPD)CT 特征与肺功能指标的相关性。方法收集COPD 患者80例,通过肺功能仪检测(PFT)和多层螺旋 CT(MSCT)检查,分析其 COPD CT 特征(像素指数)与肺功能指标[1秒用力呼气容积(FEV1)、第1秒用力呼气容积占用力肺活量百分比(FEV1/FVC)、残气/肺总量比(RV /TLC)]的相关性。结果根据 CT 测量肺密度减低区域面积(LAA%)和气道壁厚度/管腔面积,将COPD 分为肺气肿表型56例、气道表型13例和混合表型11例,肺气肿表型像素指数、FEV1、FEV1/FVC、RV /TLC 分别为27.68%、(32.19±16.78)%、(43.69±11.23)、(55.67±15.49),气道表型分别为5.23%、(55.67±23.12)%、(52.30±10.67)、(49.48±13.27),混合表型分别为22.47%、(41.23±12.55)%、(47.31±9.98)、(54.19±16.29),像素指数、FEV1、FEV1/FVC、RV /TLC 在 COPD CT 不同表型间差异均有统计学意义(χ2=19.013,F =6.234、7.854、6.389,均 P <0.05);肺气肿表型和气道表型中像素指数与 FEV1和FEV1/FVC 呈负相关(r =-0.67、-0.94、-0.55、-0.42,均 P <0.05),与 RV /TLC 呈现正相关关系(r =0.57、0.37,均 P <0.05);混合表型中像素指数与 FEV1、FEV1/FVC 和 RV /TLC 均无明显相关关系(r =-0.56、-0.27、0.32,均 P >0.05)。结论CT 特征可以作为诊断 COPD 分类和治疗效果参考依据,主要在肺气肿表型和气道表型中 PFT 复查意义较大。
目的:探討不同慢性阻塞性肺疾病(COPD)CT 特徵與肺功能指標的相關性。方法收集COPD 患者80例,通過肺功能儀檢測(PFT)和多層螺鏇 CT(MSCT)檢查,分析其 COPD CT 特徵(像素指數)與肺功能指標[1秒用力呼氣容積(FEV1)、第1秒用力呼氣容積佔用力肺活量百分比(FEV1/FVC)、殘氣/肺總量比(RV /TLC)]的相關性。結果根據 CT 測量肺密度減低區域麵積(LAA%)和氣道壁厚度/管腔麵積,將COPD 分為肺氣腫錶型56例、氣道錶型13例和混閤錶型11例,肺氣腫錶型像素指數、FEV1、FEV1/FVC、RV /TLC 分彆為27.68%、(32.19±16.78)%、(43.69±11.23)、(55.67±15.49),氣道錶型分彆為5.23%、(55.67±23.12)%、(52.30±10.67)、(49.48±13.27),混閤錶型分彆為22.47%、(41.23±12.55)%、(47.31±9.98)、(54.19±16.29),像素指數、FEV1、FEV1/FVC、RV /TLC 在 COPD CT 不同錶型間差異均有統計學意義(χ2=19.013,F =6.234、7.854、6.389,均 P <0.05);肺氣腫錶型和氣道錶型中像素指數與 FEV1和FEV1/FVC 呈負相關(r =-0.67、-0.94、-0.55、-0.42,均 P <0.05),與 RV /TLC 呈現正相關關繫(r =0.57、0.37,均 P <0.05);混閤錶型中像素指數與 FEV1、FEV1/FVC 和 RV /TLC 均無明顯相關關繫(r =-0.56、-0.27、0.32,均 P >0.05)。結論CT 特徵可以作為診斷 COPD 分類和治療效果參攷依據,主要在肺氣腫錶型和氣道錶型中 PFT 複查意義較大。
목적:탐토불동만성조새성폐질병(COPD)CT 특정여폐공능지표적상관성。방법수집COPD 환자80례,통과폐공능의검측(PFT)화다층라선 CT(MSCT)검사,분석기 COPD CT 특정(상소지수)여폐공능지표[1초용력호기용적(FEV1)、제1초용력호기용적점용력폐활량백분비(FEV1/FVC)、잔기/폐총량비(RV /TLC)]적상관성。결과근거 CT 측량폐밀도감저구역면적(LAA%)화기도벽후도/관강면적,장COPD 분위폐기종표형56례、기도표형13례화혼합표형11례,폐기종표형상소지수、FEV1、FEV1/FVC、RV /TLC 분별위27.68%、(32.19±16.78)%、(43.69±11.23)、(55.67±15.49),기도표형분별위5.23%、(55.67±23.12)%、(52.30±10.67)、(49.48±13.27),혼합표형분별위22.47%、(41.23±12.55)%、(47.31±9.98)、(54.19±16.29),상소지수、FEV1、FEV1/FVC、RV /TLC 재 COPD CT 불동표형간차이균유통계학의의(χ2=19.013,F =6.234、7.854、6.389,균 P <0.05);폐기종표형화기도표형중상소지수여 FEV1화FEV1/FVC 정부상관(r =-0.67、-0.94、-0.55、-0.42,균 P <0.05),여 RV /TLC 정현정상관관계(r =0.57、0.37,균 P <0.05);혼합표형중상소지수여 FEV1、FEV1/FVC 화 RV /TLC 균무명현상관관계(r =-0.56、-0.27、0.32,균 P >0.05)。결론CT 특정가이작위진단 COPD 분류화치료효과삼고의거,주요재폐기종표형화기도표형중 PFT 복사의의교대。
Objective To study the correlation between CT features and pulmonary function indexes in dif-ferent chronic obstructive pulmonary diseases(COPD).Methods Collection of COPD patients with 80 cases were collected,,the correlation analysis of COPD CT features (pixel index)and pulmonary function,including one second forced expiratory volume (FEV1 ),one second forced expiratory volume accounted for the percentage of forced vital capacity (FVC)and residual volume /lung total ratio (RV /TLC)were examined by pulmonary function testing (PFT)and multislice spiral CT (MSCT).Results According to CT,the regional area of lung density (LAA%)and airway wall thickness/lumen area were measured,COPD was divided into 56 cases of emphysema phenotype,13 case of airway phenotype and 11 case of mixed phenotype.The emphysema phenotype index,FEV1 ,FEV1 /FVC pixels,RV /TLC =27.68%,(32.19 ±16.78)%,(43.69 ±11.23),(55.67 ±15.49 ),airway phenotype were 5.23%, (55.67 ±23.12)%,(52.30 ±10.67),(49.48 ±13.27),respectively,mixed phenotype were 22.47% (41.23 ± 12.55)%,(47.31 ±9.98),(54.19 ±16.29),FEV1 ,FEV1 /FVC,pixel index,RV /TLC COPD CT in different phe-notypic differences were statistically significant (χ2 =19.013,F =6.234,7.854,6.389,all P <0.05).The emphyse-ma phenotype and airway phenotype in pixel index and FEV1 and FEV1 /FVC were negative correlation (r =-0.67,-0.94,-0.55,-0.42,all P <0.05),showed a positive correlation with RV /TLC (r =0.57,0.37,all P <0.05). Mixed pixel phenotype index and FEV1 ,FEV1 /FVC and RV /TLC were not significantly correlated (r =-0.56,-0.27,0.32,all P >0.05).Conclusion CT features can be regarded as the reference to diagnosis the COPD pheno-type and evaluate the effect of treatment,it is necessary to re -examine PFT in emphysema and airway phenotypes.