CAJ | 학술논문

目的：探讨马来酸桂哌奇特治疗不稳定性心绞痛的临床疗效。方法：将80例不稳定性心绞痛患者随机分成观察组和对照组，各40例。对照组给予血管紧张素转换酶抑制剂、钙离子拮抗剂及β受体阻滞剂、硝酸酯类及抗血小板聚集、阿司匹林进行治疗，观察组在对照组的基础上加用马来酸桂哌奇特治疗。结果：观察组总有效率97.5%明显优于对照组的70.0%(P＜0.05)；两组患者治疗后血液流变学水平和CRP水平明显低于治疗前(P＜0.05)，观察组治疗后血液流变学水平和CRP水平明显优于对照组(P＜0.05)。结论：马来酸桂哌奇特治疗不稳定性心绞痛临床疗效显著。
목적：탐토마래산계고기특치료불은정성심교통적림상료효。방법：장80례불은정성심교통환자수궤분성관찰조화대조조，각40례。대조조급여혈관긴장소전환매억제제、개리자길항제급β수체조체제、초산지류급항혈소판취집、아사필림진행치료，관찰조재대조조적기출상가용마래산계고기특치료。결과：관찰조총유효솔97.5%명현우우대조조적70.0%(P＜0.05)；량조환자치료후혈액류변학수평화CRP수평명현저우치료전(P＜0.05)，관찰조치료후혈액류변학수평화CRP수평명현우우대조조(P＜0.05)。결론：마래산계고기특치료불은정성심교통림상료효현저。
Objective:To explore the clinical curative effect of cinepazide maleate in the treatment of unstable angina pectoris. Methods:80 patients with unstable angina pectoris were randomly divided into the observation group and the control group with 40 cases in each.The control group were given angiotensin converting enzyme inhibitors,calcium ion antagonist,beta blockers,nitrates, antiplatelet aggregation and aspirin treatment.The observation group were given cinepazide maleate treatment on the basis of the control group.Results:The total effective rate(97.5%) of the observation group was significantly better than 70.0% of the control group(P<0.05).The hemorrheology levels and CRP levels of patients in two groups after treatment were significantly lower than those before treatment(P<0.05).The hemorrheology level and CRP level the observation group after treatment were significantly better than those of the control group(P<0.05).Conclusion:Cinepazide maleate in the treatment of unstable angina pectoris has significant clinical curative effect.