中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2015年
23期
2779-2782
,共4页
符国良%孟志斌%李俊%吉貞料
符國良%孟誌斌%李俊%吉貞料
부국량%맹지빈%리준%길정료
脊柱炎, 强直性%脊柱骨折%危险因素
脊柱炎, 彊直性%脊柱骨摺%危險因素
척주염, 강직성%척주골절%위험인소
Spondylitis,ankylosing%Spinal fracture%Risk factors
目的:对强直性脊柱炎( AS)患者进行临床资料分析,探究其发生脊柱骨折的危险因素。方法采用病例对照研究方法,选取2009年1月—2013年12月在海南医学院附属医院就诊的AS患者134例,以发生脊柱骨折患者为病例组,共25例;以未发生脊柱骨折患者为对照组,共109例。测量患者指-地距离、 Schober 指数、 BASRI分数;检测血清C反应蛋白( CRP)、红细胞沉降率( ESR);测量全身及各部分骨密度( BMD) T-score值。测定部位主要为:全身BMD T-score,腰椎(LS) BMD T-score,股骨颈(FN) BMD T-score。结果两组患者性别、体质指数( BMI)、病程、 BASRI分数、 CRP、 ESR、全身BMD T-score、 LS-BMD T-score、 FN-BMD T-score比较,差异均无统计学意义(P>0.05)。两组年龄、跌落创伤史、指-地距离、 Schober 指数比较,差异均有统计学意义(P<0.05)。多因素Logistic 回归分析结果显示,性别、跌落创伤史、病程、 Schober 指数、 ESR、 LS-BMD T -score 和FN-BMD T-score为影响AS患者发生脊柱骨折的因素( P<0.05)。结论男性、跌落创伤史、 ESR高、病程长、Schober指数低、 LS-BMD T-score和FN-BMD T-score值低、指-地距离长的AS患者可能更容易发生脊柱骨折,应提前做好预防,及时控制病情,改善体内骨代谢情况,治疗骨量减少和骨质疏松。
目的:對彊直性脊柱炎( AS)患者進行臨床資料分析,探究其髮生脊柱骨摺的危險因素。方法採用病例對照研究方法,選取2009年1月—2013年12月在海南醫學院附屬醫院就診的AS患者134例,以髮生脊柱骨摺患者為病例組,共25例;以未髮生脊柱骨摺患者為對照組,共109例。測量患者指-地距離、 Schober 指數、 BASRI分數;檢測血清C反應蛋白( CRP)、紅細胞沉降率( ESR);測量全身及各部分骨密度( BMD) T-score值。測定部位主要為:全身BMD T-score,腰椎(LS) BMD T-score,股骨頸(FN) BMD T-score。結果兩組患者性彆、體質指數( BMI)、病程、 BASRI分數、 CRP、 ESR、全身BMD T-score、 LS-BMD T-score、 FN-BMD T-score比較,差異均無統計學意義(P>0.05)。兩組年齡、跌落創傷史、指-地距離、 Schober 指數比較,差異均有統計學意義(P<0.05)。多因素Logistic 迴歸分析結果顯示,性彆、跌落創傷史、病程、 Schober 指數、 ESR、 LS-BMD T -score 和FN-BMD T-score為影響AS患者髮生脊柱骨摺的因素( P<0.05)。結論男性、跌落創傷史、 ESR高、病程長、Schober指數低、 LS-BMD T-score和FN-BMD T-score值低、指-地距離長的AS患者可能更容易髮生脊柱骨摺,應提前做好預防,及時控製病情,改善體內骨代謝情況,治療骨量減少和骨質疏鬆。
목적:대강직성척주염( AS)환자진행림상자료분석,탐구기발생척주골절적위험인소。방법채용병례대조연구방법,선취2009년1월—2013년12월재해남의학원부속의원취진적AS환자134례,이발생척주골절환자위병례조,공25례;이미발생척주골절환자위대조조,공109례。측량환자지-지거리、 Schober 지수、 BASRI분수;검측혈청C반응단백( CRP)、홍세포침강솔( ESR);측량전신급각부분골밀도( BMD) T-score치。측정부위주요위:전신BMD T-score,요추(LS) BMD T-score,고골경(FN) BMD T-score。결과량조환자성별、체질지수( BMI)、병정、 BASRI분수、 CRP、 ESR、전신BMD T-score、 LS-BMD T-score、 FN-BMD T-score비교,차이균무통계학의의(P>0.05)。량조년령、질락창상사、지-지거리、 Schober 지수비교,차이균유통계학의의(P<0.05)。다인소Logistic 회귀분석결과현시,성별、질락창상사、병정、 Schober 지수、 ESR、 LS-BMD T -score 화FN-BMD T-score위영향AS환자발생척주골절적인소( P<0.05)。결론남성、질락창상사、 ESR고、병정장、Schober지수저、 LS-BMD T-score화FN-BMD T-score치저、지-지거리장적AS환자가능경용역발생척주골절,응제전주호예방,급시공제병정,개선체내골대사정황,치료골량감소화골질소송。
Objective To analyze the clinical data of AS patients and investigate the risk factors for their spinal fracture.Methods In this case-control study, we enrolled 134 AS patients who received treatment in the Affiliated Hospital of Hainan Medical College from January 2009 to December 2013.We assigned 25 patients with spinal fracture into the case group and 109 patients without spinal fracture into control group .Finger-earth distance , Schober index and BASRI score were measured;CRP and ESR levels were tested; bone mineral density ( BMD) T-scores of whole body and some segments were measured , mainly including systemic BMD T -score, LS BMD T -score and FN BMD T -score.Results The two groups were not significantly different (P>0.05) in gender, BMI, disease course, BASRI score, CRP, ESR, systemic BMD T-score, LS BMD T-score and FN BMD T -score.The two groups were significant different (P <0.05) in age, history of tumbling trauma, finger-earth distance and Schober index .The multivariate Logistic regression analysis showed that gender , history of tumbling trauma, disease course, Schober index, ESR, LS-BMD T-score and FN-BMD T-score were influencing factors for spinal fracture in AS patients (P<0.05).Conclusion Male, history of tumbling trauma, high ESR, long disease course, low Schober index, low LS-BMD T-score, low FN-BMD T-score and high finger-earth distance are associated with more possibility of spinal fracture in AS patients .In these cases , precaution should be made in advance and the disease should be controlled in time, in order to improve bone metabolism and reduce osteopenia and osteoporosis .