中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2015年
23期
2776-2778,2779
,共4页
顾春江%陶初华%丁伟国%俞钰贤%王崇佳
顧春江%陶初華%丁偉國%俞鈺賢%王崇佳
고춘강%도초화%정위국%유옥현%왕숭가
脊髓损伤%交叉感染%肺炎%影响因素分析
脊髓損傷%交扠感染%肺炎%影響因素分析
척수손상%교차감염%폐염%영향인소분석
Spinal cord injuries%Cross infection%Pneumonia%Root cause analysis
目的:分析颈髓损伤患者医院获得性肺炎( HAP)的发病情况,探讨其影响因素,为预防HAP提供参考。方法本研究采用前瞻性研究方法,选择2010年3月—2014年3月在桐乡市第一人民医院住院治疗的358例颈髓损伤患者为研究对象。依据是否发生HAP分为HAP组和非HAP组,采用单因素分析和Logistic回归分析探讨颈髓损伤患者发生HAP的影响因素。结果 HAP多发生在颈髓损伤后72.0~96.0 h,平均(86.5±11.9) h;颈髓损伤患者HAP的发生率为30.2%(108例)。 HAP组(n =108)和非HAP组(n=250)的年龄、损伤节段、日本骨科协会(JOA)评分、低蛋白血症、低氧血症、伤后8.0 h内行甲泼尼龙治疗、机械通气、气管切开率和住院时间比较,差异均有统计学意义(P<0.05)。 Logistic 回归分析结果显示,气管切开(OR=4.345, P<0.001)、 JOA 评分(OR=3.213, P=0.004)、机械通气(OR=2.375, P=0.012)、损伤节段(OR=1.847, P=0.023)和住院时间(OR=1.235, P=0.031)均为颈髓损伤患者HAP的独立影响因素。结论颈髓损伤患者HAP发生率较高,气管切开、 JOA评分、机械通气、损伤节段和住院时间为其影响因素。
目的:分析頸髓損傷患者醫院穫得性肺炎( HAP)的髮病情況,探討其影響因素,為預防HAP提供參攷。方法本研究採用前瞻性研究方法,選擇2010年3月—2014年3月在桐鄉市第一人民醫院住院治療的358例頸髓損傷患者為研究對象。依據是否髮生HAP分為HAP組和非HAP組,採用單因素分析和Logistic迴歸分析探討頸髓損傷患者髮生HAP的影響因素。結果 HAP多髮生在頸髓損傷後72.0~96.0 h,平均(86.5±11.9) h;頸髓損傷患者HAP的髮生率為30.2%(108例)。 HAP組(n =108)和非HAP組(n=250)的年齡、損傷節段、日本骨科協會(JOA)評分、低蛋白血癥、低氧血癥、傷後8.0 h內行甲潑尼龍治療、機械通氣、氣管切開率和住院時間比較,差異均有統計學意義(P<0.05)。 Logistic 迴歸分析結果顯示,氣管切開(OR=4.345, P<0.001)、 JOA 評分(OR=3.213, P=0.004)、機械通氣(OR=2.375, P=0.012)、損傷節段(OR=1.847, P=0.023)和住院時間(OR=1.235, P=0.031)均為頸髓損傷患者HAP的獨立影響因素。結論頸髓損傷患者HAP髮生率較高,氣管切開、 JOA評分、機械通氣、損傷節段和住院時間為其影響因素。
목적:분석경수손상환자의원획득성폐염( HAP)적발병정황,탐토기영향인소,위예방HAP제공삼고。방법본연구채용전첨성연구방법,선택2010년3월—2014년3월재동향시제일인민의원주원치료적358례경수손상환자위연구대상。의거시부발생HAP분위HAP조화비HAP조,채용단인소분석화Logistic회귀분석탐토경수손상환자발생HAP적영향인소。결과 HAP다발생재경수손상후72.0~96.0 h,평균(86.5±11.9) h;경수손상환자HAP적발생솔위30.2%(108례)。 HAP조(n =108)화비HAP조(n=250)적년령、손상절단、일본골과협회(JOA)평분、저단백혈증、저양혈증、상후8.0 h내행갑발니룡치료、궤계통기、기관절개솔화주원시간비교,차이균유통계학의의(P<0.05)。 Logistic 회귀분석결과현시,기관절개(OR=4.345, P<0.001)、 JOA 평분(OR=3.213, P=0.004)、궤계통기(OR=2.375, P=0.012)、손상절단(OR=1.847, P=0.023)화주원시간(OR=1.235, P=0.031)균위경수손상환자HAP적독립영향인소。결론경수손상환자HAP발생솔교고,기관절개、 JOA평분、궤계통기、손상절단화주원시간위기영향인소。
Objective To investigate the incidence of hospital acquired pneumonia ( HAP) in patients with cervical spinal cord injury (CSCI) and explore its influencing factors , in order to provide references for the prevention of HAP .Methods In this prospective study , we enrolled 358 patients with CSCI who were admitted into the First People′s Hospital of Tongxiang from March, 2010 to March, 2014.According to whether HAP occurred , the subjects were divided into two groups: HAP group and non-HAP group.Univariate analysis and Logistic regression analysis were conducted to investigate influencing factors for HAP in patients with CSCI .Results HAP mostly occurred 72.0 to 96.0 hours after CSCI occurred , with an average time range of (86.5 ±11.9) hours.The incidence rate of HAP was 30.2% (108 cases).The HAP group (n=108) and non-HAP group (n =250) were significantly different (P <0.05) in age, injury segment, JOA score, hypoproteinemia, hypoxemia , methylprednisolone treatment within 8.0 hours after injury , mechanical ventilation , tracheotomy and hospitalization time .Logistic regression analysis showed that the tracheotomy (OR=4.345, P<0.001), JOA score (OR=3.213, P=0.004), mechanical ventilation (OR=2.375, P=0.012), injury segment (OR=1.847, P=0.023) and hospitalization time (OR=1.235, P=0.031) were independent influencing factors for HAP in CSCI patients .Conclusion The incidence of HAP is high in CSCI patients, and tracheotomy, JOA score, mechanical ventilation, injury segment and hospitalization time are influencing factors for HAP in CSCI patients .