中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2015年
23期
2787-2791
,共5页
李晨曦%张小倩%章秋%代芳%何勇%胡红琳%陈明卫%邓大同%左春林%王长江
李晨晞%張小倩%章鞦%代芳%何勇%鬍紅琳%陳明衛%鄧大同%左春林%王長江
리신희%장소천%장추%대방%하용%호홍림%진명위%산대동%좌춘림%왕장강
性腺功能减退症%男性%人格%自卑感%心理健康
性腺功能減退癥%男性%人格%自卑感%心理健康
성선공능감퇴증%남성%인격%자비감%심리건강
Hypogonadism%Male%Personality%Inferiority%Mental health
目的:了解男性特发性低促性腺激素性性腺功能减退症( IHH)患者的心理健康状况。方法选取2012年1月—2015年1月在安徽医科大学第一附属医院内分泌科住院诊治的男性 IHH患者38例( IHH组),另选取同期在本院体检的健康男性青年20例为对照组。测定两组双侧睾丸容积、阴茎长度、性激素〔卵泡刺激素( FSH)、黄体生成素(LH)、睾酮(T)〕、血脂〔总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇( HDL-C)〕、空腹血糖、空腹胰岛素、25羟维生素D等水平,并运用艾森克个性问卷( EPQ)、自卑感量表(FIS)、症状自评量表(SCL-90)评定两组心理健康状况。结果两组年龄、 BMI、 TC、 LDL-C、 HDL-C、空腹血糖和25羟维生素D比较,差异均无统计学意义( P>0.05); IHH组睾丸左侧容积、睾丸右侧容积、阴茎长度、FSH、 LH、 T均低于对照组; TG、空腹胰岛素和胰岛素抵抗指数( HOMA-IR)均高于对照组( P<0.05)。 EPQ:两组内外向(E)、精神质(P)和掩饰性(L)评分比较,差异无统计学意义(P>0.05); IHH组神经质(N)评分高于对照组(P<0.05)。 FIS:两组学习能力评分比较,差异无统计学意义(P>0.05); IHH组自我价值、社交自信、外貌自信、体能自信和FIS量表总分均高于对照组( P<0.05)。 SCL-90: IHH组躯体化、强迫、人际关系敏感、抑郁、焦虑、敌对、恐惧、偏执、精神病性、其他因子评分及总分均高于对照组( P<0.05)。 SCL-90总分与N ( r=0.844, P<0.001)、 P ( r =0.733, P =0.003)、自我价值( r =0.748, P =0.002)、社交自信( r =0.551, P =0.041)、外貌自信( r=0.687, P=0.007)呈正相关。多元线性回归分析结果显示, N和自我价值是影响IHH患者心理健康的因素( P<0.05)。结论男性IHH患者心理健康水平低于正常人群,伴有N、自我价值因子评分较高的患者更容易发生心理问题。
目的:瞭解男性特髮性低促性腺激素性性腺功能減退癥( IHH)患者的心理健康狀況。方法選取2012年1月—2015年1月在安徽醫科大學第一附屬醫院內分泌科住院診治的男性 IHH患者38例( IHH組),另選取同期在本院體檢的健康男性青年20例為對照組。測定兩組雙側睪汍容積、陰莖長度、性激素〔卵泡刺激素( FSH)、黃體生成素(LH)、睪酮(T)〕、血脂〔總膽固醇(TC)、三酰甘油(TG)、低密度脂蛋白膽固醇(LDL-C)、高密度脂蛋白膽固醇( HDL-C)〕、空腹血糖、空腹胰島素、25羥維生素D等水平,併運用艾森剋箇性問捲( EPQ)、自卑感量錶(FIS)、癥狀自評量錶(SCL-90)評定兩組心理健康狀況。結果兩組年齡、 BMI、 TC、 LDL-C、 HDL-C、空腹血糖和25羥維生素D比較,差異均無統計學意義( P>0.05); IHH組睪汍左側容積、睪汍右側容積、陰莖長度、FSH、 LH、 T均低于對照組; TG、空腹胰島素和胰島素牴抗指數( HOMA-IR)均高于對照組( P<0.05)。 EPQ:兩組內外嚮(E)、精神質(P)和掩飾性(L)評分比較,差異無統計學意義(P>0.05); IHH組神經質(N)評分高于對照組(P<0.05)。 FIS:兩組學習能力評分比較,差異無統計學意義(P>0.05); IHH組自我價值、社交自信、外貌自信、體能自信和FIS量錶總分均高于對照組( P<0.05)。 SCL-90: IHH組軀體化、彊迫、人際關繫敏感、抑鬱、焦慮、敵對、恐懼、偏執、精神病性、其他因子評分及總分均高于對照組( P<0.05)。 SCL-90總分與N ( r=0.844, P<0.001)、 P ( r =0.733, P =0.003)、自我價值( r =0.748, P =0.002)、社交自信( r =0.551, P =0.041)、外貌自信( r=0.687, P=0.007)呈正相關。多元線性迴歸分析結果顯示, N和自我價值是影響IHH患者心理健康的因素( P<0.05)。結論男性IHH患者心理健康水平低于正常人群,伴有N、自我價值因子評分較高的患者更容易髮生心理問題。
목적:료해남성특발성저촉성선격소성성선공능감퇴증( IHH)환자적심리건강상황。방법선취2012년1월—2015년1월재안휘의과대학제일부속의원내분비과주원진치적남성 IHH환자38례( IHH조),령선취동기재본원체검적건강남성청년20례위대조조。측정량조쌍측고환용적、음경장도、성격소〔란포자격소( FSH)、황체생성소(LH)、고동(T)〕、혈지〔총담고순(TC)、삼선감유(TG)、저밀도지단백담고순(LDL-C)、고밀도지단백담고순( HDL-C)〕、공복혈당、공복이도소、25간유생소D등수평,병운용애삼극개성문권( EPQ)、자비감량표(FIS)、증상자평량표(SCL-90)평정량조심리건강상황。결과량조년령、 BMI、 TC、 LDL-C、 HDL-C、공복혈당화25간유생소D비교,차이균무통계학의의( P>0.05); IHH조고환좌측용적、고환우측용적、음경장도、FSH、 LH、 T균저우대조조; TG、공복이도소화이도소저항지수( HOMA-IR)균고우대조조( P<0.05)。 EPQ:량조내외향(E)、정신질(P)화엄식성(L)평분비교,차이무통계학의의(P>0.05); IHH조신경질(N)평분고우대조조(P<0.05)。 FIS:량조학습능력평분비교,차이무통계학의의(P>0.05); IHH조자아개치、사교자신、외모자신、체능자신화FIS량표총분균고우대조조( P<0.05)。 SCL-90: IHH조구체화、강박、인제관계민감、억욱、초필、활대、공구、편집、정신병성、기타인자평분급총분균고우대조조( P<0.05)。 SCL-90총분여N ( r=0.844, P<0.001)、 P ( r =0.733, P =0.003)、자아개치( r =0.748, P =0.002)、사교자신( r =0.551, P =0.041)、외모자신( r=0.687, P=0.007)정정상관。다원선성회귀분석결과현시, N화자아개치시영향IHH환자심리건강적인소( P<0.05)。결론남성IHH환자심리건강수평저우정상인군,반유N、자아개치인자평분교고적환자경용역발생심리문제。
Objective To investigate the mental health status of male patients with idiopathic hypogonadotropic hypogonadism ( IHH) .Methods We enrolled 38 male IHH patients who received hospitalized treatment from the Department of Endocrinology of the First Affiliated Hospital of Anhui Medical University from January 2012 to January 2015 as the IHH group.Another 20 healthy young males who received physical examination in the same hospital during the same period were enrolled as the control group.Bilateral testicular volume, penial length, follicle -stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), TC, TG, LDL -C, HDL -C, fasting blood glucose, fasting insulin, 25 (OH) -Vitamin D were measured and compared between the two groups .EPQ, FIS and SCL-90 scale were used to determine mental health status of the two groups .Results There was no significant difference (P>0.05) between the two groups in age , BMI, TC, LDL-C, HDL-C, fasting blood glucose and 25 ( OH) -Vitamin D; the IHH group was lower ( P<0.05 ) in left testicular volume, right testicular volume, penial length, FSH, LH and T and higher (P<0.05) in TG, fasting insulin and HOMA-IR than the control group.For EPQ results, there was no significant difference (P>0.05) between the two groups in the scores of E, P and L, and the IHH group was higher (P<0.05) than the control group in the score of N.For FIS results, there was no significant difference between the two groups in the score of learning ability ( P>0.05 ) , and the IHH group was higher (P<0.05) than the control group in self -value, social self -confidence, self -confidence of appearance , self -confidence of physical strength and total score .For SCL -90 scale results , the IHH group was higher ( P <0.05 ) than the control group in somatization , compulsiveness, sensitiveness of interpersonal relationship , depression, anxiety, antagonism, fear, bigotry, psychosis, the scores of other and the total score .The total score of SCL -90 was positively correlated with N (r=0.844, P<0.001), P (r=0.733, P=0.003), self-value (r=0.748, P=0.002), social confidence (r=0.551, P=0.041) and self-confidence of appearance (r=0.687, P=0.007).The multivariate linear regression analysis showed that N and self-value were influencing factors for the mental health status of IHH patients ( P<0.05).Conclusion Male IHH patients are lower than healthy people in mental health status , and higher scores of N and self -value are associated with higher incidence of mental problems in IHH patients .