CAJ | 학술논문

经皮冠状动脉介入（PCI）术后患者接受双联抗血小板治疗（DAPT）可有效降低支架内再狭窄（ISR）的发生风险，但同样并存出血的风险。如何决策DAPT的持续时间，以在血栓与出血间保持平衡，始终是心脏科医生面临的难题。持续至少1年的DAPT方案已经成为PCI术后患者的标准治疗方案，并被列入多个指南。最新《欧洲冠状动脉血运重建指南》对于DAPT持续时间进行了相应的改动，建议部分患者接受短期DAPT。本文对近年有关缩短DAPT持续时间及延长DAPT持续时间的大型临床试验进行梳理，以期为临床医师提供参考。
경피관상동맥개입（PCI）술후환자접수쌍련항혈소판치료（DAPT）가유효강저지가내재협착（ISR）적발생풍험，단동양병존출혈적풍험。여하결책DAPT적지속시간，이재혈전여출혈간보지평형，시종시심장과의생면림적난제。지속지소1년적DAPT방안이경성위PCI술후환자적표준치료방안，병피렬입다개지남。최신《구주관상동맥혈운중건지남》대우DAPT지속시간진행료상응적개동，건의부분환자접수단기DAPT。본문대근년유관축단DAPT지속시간급연장DAPT지속시간적대형림상시험진행소리，이기위림상의사제공삼고。
Dual anti-platelet therapy (DAPT) after percutaneous coronary intervention (PCI) can effectively reduce the risk of in -stent restenosis ( ISR), while there is also risk of hemorrhage .The determination of DAPT duration and the balance between thrombus and hemorrhage have been the major concerns for cardiologists .DAPT lasting for at least 1 year has become the standard therapy for patients undergoing PCI and is recommended in many guidelines .The latest European guideline for coronary artery revascularization adjusts DAPT duration and recommends that short -term DAPT should be conducted on a portion of patients .The paper reviewed the large -scale clinical trials relevant with shortening or prolonging DAPT duration , in order to provide references for clinical doctors .