医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2015年
31期
38-38,39
,共2页
地佐辛%氟比洛芬酯%舒芬太尼%静脉自控镇痛%痔疮手术
地佐辛%氟比洛芬酯%舒芬太尼%靜脈自控鎮痛%痔瘡手術
지좌신%불비락분지%서분태니%정맥자공진통%치창수술
Dezocine%Flurbiprofen%Sufentanil%Patients control intravenous analgesia(PCIA)%Hemor hoids surgery
目的观察地佐辛复合氟比洛芬酯与舒芬太尼用于痔疮术后静脉自控镇痛的效果及安全性比较。方法选择肛肠科择期行痔疮手术的成年患者60例，ASAⅠ~Ⅱ级，随机均分为地佐辛复合氟比洛芬酯组(DF组)和舒芬太尼组(S组)，两组患者均在单次腰麻下行手术，绝对麻醉平面固定到胸10水平。两组患者术毕行静脉自控镇痛(PCIA)，DF组镇痛泵配方为地佐辛30mg+氟比洛芬酯150mg，S组为舒芬太尼0.001mg/(d·kg)，两组均加生理盐水配至100ml。术后记录2、4、8、12、24、48h各时间点患者的VAS评分、Ramsay镇静评分和不良反应的发生情况，有效按压次数及补救性镇痛药物的量。结果两组患者术后VAS评分、Ramsay镇静评分和有效按压次数在术后48h内差异均无统计学意义，两组均未行补救治疗。 DF组不良反应明显少于S组(<0.05)。结论与舒芬太尼比较，地佐辛复合氟比洛芬酯能更安全有效的用于痔疮患者术后镇痛。
目的觀察地佐辛複閤氟比洛芬酯與舒芬太尼用于痔瘡術後靜脈自控鎮痛的效果及安全性比較。方法選擇肛腸科擇期行痔瘡手術的成年患者60例，ASAⅠ~Ⅱ級，隨機均分為地佐辛複閤氟比洛芬酯組(DF組)和舒芬太尼組(S組)，兩組患者均在單次腰痳下行手術，絕對痳醉平麵固定到胸10水平。兩組患者術畢行靜脈自控鎮痛(PCIA)，DF組鎮痛泵配方為地佐辛30mg+氟比洛芬酯150mg，S組為舒芬太尼0.001mg/(d·kg)，兩組均加生理鹽水配至100ml。術後記錄2、4、8、12、24、48h各時間點患者的VAS評分、Ramsay鎮靜評分和不良反應的髮生情況，有效按壓次數及補救性鎮痛藥物的量。結果兩組患者術後VAS評分、Ramsay鎮靜評分和有效按壓次數在術後48h內差異均無統計學意義，兩組均未行補救治療。 DF組不良反應明顯少于S組(<0.05)。結論與舒芬太尼比較，地佐辛複閤氟比洛芬酯能更安全有效的用于痔瘡患者術後鎮痛。
목적관찰지좌신복합불비락분지여서분태니용우치창술후정맥자공진통적효과급안전성비교。방법선택항장과택기행치창수술적성년환자60례，ASAⅠ~Ⅱ급，수궤균분위지좌신복합불비락분지조(DF조)화서분태니조(S조)，량조환자균재단차요마하행수술，절대마취평면고정도흉10수평。량조환자술필행정맥자공진통(PCIA)，DF조진통빙배방위지좌신30mg+불비락분지150mg，S조위서분태니0.001mg/(d·kg)，량조균가생리염수배지100ml。술후기록2、4、8、12、24、48h각시간점환자적VAS평분、Ramsay진정평분화불량반응적발생정황，유효안압차수급보구성진통약물적량。결과량조환자술후VAS평분、Ramsay진정평분화유효안압차수재술후48h내차이균무통계학의의，량조균미행보구치료。 DF조불량반응명현소우S조(<0.05)。결론여서분태니비교，지좌신복합불비락분지능경안전유효적용우치창환자술후진통。
Objective To investigate the ef ects of dezocine combined with flurbiprofen and sufentanil for patients control intravenous analgesia (PCIA)after Hemorrhoids surgeries.Methods Sixty patients scheduled for selective Hemor hoids surgeries were randomly divided into dezocine combined with flurbiprofen group(group DF)and sufentanil group(group S),each group of 30 cases,two groups of patients were in single spinal anesthesia surgery,absolutely anesthesia plane fixed to the level 10 of the chest,were given patient-control ed intravenous analgesia (PCIA)after Hemor hoids surgery. Patients in group DF were given dezocine 30 mg+flurbiprofen 150 mg+0.9%NaCl=100ml;Patients in group S were given sufentanil 0.001mg/(d·kg).Visual analogue scores (VAS),Ramsay score,the ef ective number of PCA,the side ef ects (nausea,vomiting,dizziness,respiratory depression and so on)and the amount of salvage analgesic drugs were recorded at 2,4,8,12,24,48 h postoperatively.Results The postoperative VAS score,Ramsay score and the number of ef ective press were no significant dif erences between two groups,the two groups were not treated by the treatment.The adverse reactions of the DF group were significantly less than that of the S group ( <0.05).Conclusion Compared with sufentanil,dezocine combined with flurbiprofen can be more safe and ef ective for postoperative analgesia in patients with Hemor hoids surgery.
