中医药学报
中醫藥學報
중의약학보
ACTA CHINESE MEDICINE AND PHARMACOLOGY
2015年
4期
9-11
,共3页
陈效忠%张艳%罗昆%常鑫%吕红梅
陳效忠%張豔%囉昆%常鑫%呂紅梅
진효충%장염%라곤%상흠%려홍매
北豆根%生物碱%化学成分
北豆根%生物堿%化學成分
북두근%생물감%화학성분
Menispermum dauricum%Alkaliod%Chemical components
目的：运用化学筛选的方法（ LC－MS n ）研究北豆根中微量生物碱类化合物。方法：采用经典的酸提碱沉法获得蝙蝠葛总生物碱，利用多种色谱法相结合分离生物碱类化合物，NMR鉴定化合物结构。结果：从北豆根中分离得到4个微量生物碱类化合物，化合物1－4经波谱鉴定分别为cissampentin，cost-aricine，cycleatjehenine，2－N－Methyltelobine。结论：化合物1－4为从该植物中首次分离得到。
目的：運用化學篩選的方法（ LC－MS n ）研究北豆根中微量生物堿類化閤物。方法：採用經典的痠提堿沉法穫得蝙蝠葛總生物堿，利用多種色譜法相結閤分離生物堿類化閤物，NMR鑒定化閤物結構。結果：從北豆根中分離得到4箇微量生物堿類化閤物，化閤物1－4經波譜鑒定分彆為cissampentin，cost-aricine，cycleatjehenine，2－N－Methyltelobine。結論：化閤物1－4為從該植物中首次分離得到。
목적：운용화학사선적방법（ LC－MS n ）연구북두근중미량생물감류화합물。방법：채용경전적산제감침법획득편복갈총생물감，이용다충색보법상결합분리생물감류화합물，NMR감정화합물결구。결과：종북두근중분리득도4개미량생물감류화합물，화합물1－4경파보감정분별위cissampentin，cost-aricine，cycleatjehenine，2－N－Methyltelobine。결론：화합물1－4위종해식물중수차분리득도。
Objective:Trace alkaloids from Menispermum dauricum can be obtained by using chemical screening ( LC-MSn ) .Methods: The roots of Menispermum dauricum were extracted and total akaloids were obtained.The total akaloids were separated by column chromatography.The structures of the compounds were established by NMR spectra. Results: Four trace alkaloid compounds named cissampentin, costaricine, cycleatjehenine and 2-N-Methyltelobine were isolated from the plant.Conclution:Compounds 1-4 are obtained from the plant for the first time.
