中国继续医学教育
中國繼續醫學教育
중국계속의학교육
CHINA CONTINUING MEDICAL EDUCATION
2015年
20期
79-80
,共2页
帕瑞昔布钠%地佐辛%腹部手术%超前镇痛
帕瑞昔佈鈉%地佐辛%腹部手術%超前鎮痛
파서석포납%지좌신%복부수술%초전진통
Parecoxib sodium%Dezocine%Abdominal surgery%Preemptive analgesia
目的:观察腹部手术使用帕瑞昔布钠或地佐辛超前镇痛的效果和安全性。方法根据使用超前镇痛药物不同将105例择期行腹部手术患者进行分组,分别在麻醉诱导前和手术结束前给予静脉滴注帕瑞昔布钠(帕瑞昔布钠组)、地佐辛(地佐辛组),采用视觉模拟评分(VAS)评价患者镇痛效果。结果地佐辛组在术后30 min末、4 h末疼痛程度(VAS评分)低于帕瑞昔布钠组,P<0.05;帕瑞昔布钠组不良事件发生率3.85%与地佐辛组3.77%比较,P>0.05。结论帕瑞昔布钠和地佐辛组均能够有效降低术后疼痛,但后者在早期镇痛方面优于前者,值得临床对作用机制和镇痛效果继续探讨。
目的:觀察腹部手術使用帕瑞昔佈鈉或地佐辛超前鎮痛的效果和安全性。方法根據使用超前鎮痛藥物不同將105例擇期行腹部手術患者進行分組,分彆在痳醉誘導前和手術結束前給予靜脈滴註帕瑞昔佈鈉(帕瑞昔佈鈉組)、地佐辛(地佐辛組),採用視覺模擬評分(VAS)評價患者鎮痛效果。結果地佐辛組在術後30 min末、4 h末疼痛程度(VAS評分)低于帕瑞昔佈鈉組,P<0.05;帕瑞昔佈鈉組不良事件髮生率3.85%與地佐辛組3.77%比較,P>0.05。結論帕瑞昔佈鈉和地佐辛組均能夠有效降低術後疼痛,但後者在早期鎮痛方麵優于前者,值得臨床對作用機製和鎮痛效果繼續探討。
목적:관찰복부수술사용파서석포납혹지좌신초전진통적효과화안전성。방법근거사용초전진통약물불동장105례택기행복부수술환자진행분조,분별재마취유도전화수술결속전급여정맥적주파서석포납(파서석포납조)、지좌신(지좌신조),채용시각모의평분(VAS)평개환자진통효과。결과지좌신조재술후30 min말、4 h말동통정도(VAS평분)저우파서석포납조,P<0.05;파서석포납조불량사건발생솔3.85%여지좌신조3.77%비교,P>0.05。결론파서석포납화지좌신조균능구유효강저술후동통,단후자재조기진통방면우우전자,치득림상대작용궤제화진통효과계속탐토。
Objective To observe the abdominal surgery parecoxib sodium or dezocine preemptive analgesia efficacy and safety. Methods According to different use of analgesic drugs lead to 105 cases of patients undergoing elective abdominal surgery group, respectively, before the induction of anesthesia before the end of surgery and intravenous infusion of parecoxib sodium (parecoxib sodium group), dezocine (dezocine group), using a visual analog scale (VAS) evaluate the analgesic effect in patients. Results Dezocine group after 30 min late, 4 h end of pain (VAS score) was significantly lower than parecoxib sodium group, P<0.05, incidence of adverse events parecoxib sodium group 3.85%and Dezocine comparison group 3.77%, P>0.05. Conclusion Parecoxib sodium and Dezocine group were able to reduce postoperative pain, but the latter than the former in early analgesia, is worthy of the mechanism of action and to continue to explore the analgesic effect.