CAJ | 학술논문

目的：观察瑞格列奈与甘精胰岛素联用治疗2型糖尿病的临床疗效。方法选取2011年4～12月在我院泌尿科治疗的105例2型糖尿病患者，随机分为实验组（瑞格列奈与甘精胰岛素联用组）55例和对照组（诺和灵组）50例，治疗结束后，比较两组患者血糖达标的时间及糖化血红蛋白值、发生低血糖的患者比例，最后统计学分析。结果实验组糖化血红蛋白的平均值为（6.1±1.1）%、血糖达标所需要的平均时间为（6.8±1.5）天、治疗过程中发生低血糖的患者比例为1.8%，均低于对照组，P均＜0.05。结论瑞格列奈与甘精胰岛素联用控制2型糖尿病患者血糖水平，疗效好，不良反应低。
목적：관찰서격렬내여감정이도소련용치료2형당뇨병적림상료효。방법선취2011년4～12월재아원비뇨과치료적105례2형당뇨병환자，수궤분위실험조（서격렬내여감정이도소련용조）55례화대조조（낙화령조）50례，치료결속후，비교량조환자혈당체표적시간급당화혈홍단백치、발생저혈당적환자비례，최후통계학분석。결과실험조당화혈홍단백적평균치위（6.1±1.1）%、혈당체표소수요적평균시간위（6.8±1.5）천、치료과정중발생저혈당적환자비례위1.8%，균저우대조조，P균＜0.05。결론서격렬내여감정이도소련용공제2형당뇨병환자혈당수평，료효호，불량반응저。
Objective To discuss the clinical effect of glargine insulin combined with repaglinide for the treatment of type 2 diabetes mellitus. Methods 105 patients with type 2 diabetes mellitus were randomly selected in our hospital from April 2011 to December, they were randomly divided into treatment group (glargine insulin combined with repaglinide treatment) 55 cases and control group (Novolin treatment) 50 cases. After the treatment, the standard blood glucose time, glycosylated hemoglobin value and the proportion of patients with hypoglycemia were compared, the results were statistical analyzed. Results In experimental group, the average value of glycosylated hemoglobin was (6.1±1.1)%, the average time of standard blood glucose was (6.8±1.5) days, the proportion of hypoglycemia patients was 1.8% during treatment, they were significantly lower than the control group, P<0.05. Conclusion Glargine insulin combined with repaglinide for treatment of type 2 diabetes mellitus can effectively control the blood glucose level and the adverse reactions are less.