CAJ | 학술논문

目的：探讨分析尼莫地平和硝普钠治疗高血压性脑病的临床疗效和不良反应。方法随机选取2009年7月～2011年10月因高血压性脑出血就诊于我院的患者130例，随机分为治疗组（采用尼莫地平治疗）65例患者，对照组（采用硝普钠治疗）65例患者，观察总结两组患者治疗的效果及不良反应发生情况，并对两组结果进行统计学分析。结果两组方法对高血压性脑病治疗均有效，但是治疗组有效率为84.6%，治疗效果好于对照组，治疗组不良反应发生率为9.2%；低于对照组，经统计分析，P＜0.05，差异有统计学意义。结论尼莫地平和硝普钠两种药物对高血压性脑病均有治疗作用，尼莫地平的治疗效果更好，并且不良反应发生率更低，更安全。
목적：탐토분석니막지평화초보납치료고혈압성뇌병적림상료효화불량반응。방법수궤선취2009년7월～2011년10월인고혈압성뇌출혈취진우아원적환자130례，수궤분위치료조（채용니막지평치료）65례환자，대조조（채용초보납치료）65례환자，관찰총결량조환자치료적효과급불량반응발생정황，병대량조결과진행통계학분석。결과량조방법대고혈압성뇌병치료균유효，단시치료조유효솔위84.6%，치료효과호우대조조，치료조불량반응발생솔위9.2%；저우대조조，경통계분석，P＜0.05，차이유통계학의의。결론니막지평화초보납량충약물대고혈압성뇌병균유치료작용，니막지평적치료효과경호，병차불량반응발생솔경저，경안전。
Objective To analyze the clinical efficacy and adverse reactions of nimodipine and sodium nitroprusside for the treatment of hypertensive encephalopathy. Methods 130 patients with hypertensive cerebral hemorrhage were randomly selected in our hospital from July 2009 to October 2011, they were randomly divided into treatment group (treated with nimodipine) 65 patients, control group (treated with sodium nitroprusside) 65 patients, the clinical efifcacy and adverse reactions were observed, the results of the two groups were statistically analyzed. Results Both of the methods were effective for the treatment of hypertensive encephalopathy, but in the treatment group, the efficiency was 84.6%. The treatment effect was significantly better than the control group. The incidence of adverse reaction was 9.2%, it was significantly lower than the control group. After statistical analysis, P<0.05, there was statistical signiifcance. Conclusion Nimodipine and sodium nitroprusside are both effective for the treatment of hypertensive encephalopathy, the effect of nimodipine is better, and the incidence of adverse reaction is lower, it is more secure.