CAJ | 학술논문

目的：建立三七、浙贝母、薏苡仁、龙血竭药材中Pb，Cu，As，Cd，Hg，Mn，Ni和Tl等18种元素检测方法，对散结镇痛胶囊中重金属元素进行控制。方法：药材采用微波消解法进行消解、电感耦合等离子体质谱仪进行分析，选择内标法定量以改善基体效应和干扰。结果：各元素的线性关系良好，相关系数R2≥0.9992；方法检出限为0.0028-0.54μg·L-1，实验重复性良好；加样回收率在73.01%-109.13%。结论：测量方法灵敏度高，专属性好，可为监控及制订中药材中有害元素的限量提供参考。
목적：건립삼칠、절패모、의이인、룡혈갈약재중Pb，Cu，As，Cd，Hg，Mn，Ni화Tl등18충원소검측방법，대산결진통효낭중중금속원소진행공제。방법：약재채용미파소해법진행소해、전감우합등리자체질보의진행분석，선택내표법정량이개선기체효응화간우。결과：각원소적선성관계량호，상관계수R2≥0.9992；방법검출한위0.0028-0.54μg·L-1，실험중복성량호；가양회수솔재73.01%-109.13%。결론：측량방법령민도고，전속성호，가위감공급제정중약재중유해원소적한량제공삼고。
To develop a method for the determination of 18 elements such as Pb, Cu, As, Hg, Mn, Ni, & Tl in Panax notoginseng,Bulbus fritillariae thunbergii,Coix seed, Resina draconis, and to control the contents of heavy metal elements in Sanjie Zhentong Capsule, the samples were digested by microwaves and then analyzed by appropriate determination parameters through ICP-MS, with the internal standard method to improve the matrix effect and interference. The correlation coefficientR2≥ 0.999 2. The lowest limits of quantification were from 0.002 8 to 0.54 μg·L-1. The experiments had better repeatability, while the recovery values ranged from 73.01% to 109.13%. The method is simple, accurate and high sensitive, and it can be used for the determination of rapid monitoring the multi-elements inPanax notoginseng, Bulbus fritillariae thunbergii, Coix seed,and Resina draconis.