CAJ | 학술논문

目的：对苯磺酸氨氯地平控制高血压患者晨峰血压和生活质量的影响进行研究。方法将120例患者根据随机数字方法分为两组，对照组60例常规治疗，观察组60例在常规治疗基础上加服苯磺酸氨氯地平，每日早上测量血压，比较患者治疗3个月后的血压以及生活质量评分情况。结果对照组患者常规治疗的总有效率68.3%，观察组患者总有效率为95.0%，观察组疗效明显优于对照组患者，两组比较差异具有统计学意义（P＜0.05）。两组患者收缩压与舒张压治疗后比治疗前均有显著降低（P＜0.05），并且治疗后观察组患者收缩压与舒张压明显低于对照组，两组比较差异具有统计学意义（P＜0.05）。治疗后患者的躯体症状、主观评分、工作表现以及智力情况具有显著改善，治疗前后比较差异具有统计学意义（P＜0.05）。而抑郁评分、生活满意度方面无显著差异（P＞0.05）。结论苯磺酸氨氯地平可以有效控制高血压患者的晨峰高血压和改善患者生活质量。
목적：대분광산안록지평공제고혈압환자신봉혈압화생활질량적영향진행연구。방법장120례환자근거수궤수자방법분위량조，대조조60례상규치료，관찰조60례재상규치료기출상가복분광산안록지평，매일조상측량혈압，비교환자치료3개월후적혈압이급생활질량평분정황。결과대조조환자상규치료적총유효솔68.3%，관찰조환자총유효솔위95.0%，관찰조료효명현우우대조조환자，량조비교차이구유통계학의의（P＜0.05）。량조환자수축압여서장압치료후비치료전균유현저강저（P＜0.05），병차치료후관찰조환자수축압여서장압명현저우대조조，량조비교차이구유통계학의의（P＜0.05）。치료후환자적구체증상、주관평분、공작표현이급지력정황구유현저개선，치료전후비교차이구유통계학의의（P＜0.05）。이억욱평분、생활만의도방면무현저차이（P＞0.05）。결론분광산안록지평가이유효공제고혈압환자적신봉고혈압화개선환자생활질량。
Objective To study the control effect of amlodipine besylate for blood pressure in morning peak and quality of life in patients with hypertension.Methods 120 cases of patients according to the random number method was divided into two <br> groups, 60 cases in the control group with routine treatment, the observation group 60 cases on the basis of conventional therapy plus service of amlodipine besylate, comparing the daily morning blood pressure measurement of patients 3 months after treatment the blood pressure and quality of life score situation.Results The total efficiency was 68.3% patients in the control group routine treatment, and the patients in the observation group the total effective rate was 95%. So the effect of observation group is obviously better than patients in the control group that was significant differences between the two groups (P﹤ 0.05). Two groups of patients with systolic and diastolic blood pressure after treatment than before treatment were significantly lower (P ﹤ 0.05), and the patients in observation group were systolic and diastolic blood pressure was lower than the control group after treatment, with significant differences between the two groups (P﹤0.05). After treatment of patients with somatic symptoms, subjective ratings, job performance and intelligence situation has improved significantly, with statistical significance before and after treatment was difference(P﹤0.05) . But there was no significant difference between depression score and life <br> satisfaction (P>0.05).Conclusion The amlodipine besylate can effective control morning peak of hypertension and improve the quality of life of patients of hypertension.