CAJ | 학술논문

目的：：回顾性分析自身抗体阴性类风湿关节炎患者的实验室及临床特点.方法：随机入选RA患者160例，分析比较自身阴性RA患者的实验室及临床特点.结果：（1）自身抗体阴性组占9.4%，三组RA患者在性别构成、平均年龄方面比较均无统计学差异.（2）在压痛关节数方面，自身抗体阴性组与其他两组比较有明显统计学差异（P<0.05）.（3）实验室指标比较，自身抗体阴性组的IgM水平显著低于其他两组，具有统计学差异（P<0.05）.结论：自身抗体阴性的类风湿关节炎患者并不少见，常出现在关节压痛数少、IgM水平低的RA患者中.
목적：：회고성분석자신항체음성류풍습관절염환자적실험실급림상특점.방법：수궤입선RA환자160례，분석비교자신음성RA환자적실험실급림상특점.결과：（1）자신항체음성조점9.4%，삼조RA환자재성별구성、평균년령방면비교균무통계학차이.（2）재압통관절수방면，자신항체음성조여기타량조비교유명현통계학차이（P<0.05）.（3）실험실지표비교，자신항체음성조적IgM수평현저저우기타량조，구유통계학차이（P<0.05）.결론：자신항체음성적류풍습관절염환자병불소견，상출현재관절압통수소、IgM수평저적RA환자중.
Objective:To analyse the laboratory and clinical features of autoantibody negative patients with rheumatoid arthritis(RA). Methods:The clinical and laboratory features parameters were compared between autoantibody nega-tive and posive group in 160 randomly selected RA patients. Results:1. The rates of autoantibody negative were 9.4%. The gender composition and average age of patients in three RA groups were no significantly differences. 2. The tender joint counts of patients in autoantibody negative group were less than other two groups(P<0.05). 3. For laboratory in-dexes, the autoantibody negative RA patients showed lower levels on IgM than other two groups(P<0.05). Conclu-sion:The autoantibody negative RA patients are not uncommon, and are more likely appear in RA patients who have tender joint counts and lower IgM levels.