CAJ | 학술논문

目的：为了观察脑出血患者病灶及周围区域葡萄糖代谢变化的规律，评价18 F-FDG PET／CT 在脑出血方面的临床应用价值。方法本研究选择经过保守干预的8名基底节区脑出血患者。在干预前和干预后30天分别行头部18 F-FDG PET／CT 扫描，对比分析干预前后出血病灶、病灶周围缺血区葡萄糖代谢变化的情况。结果干预前后，脑出血病灶区域的像素亮度值分别为：659．8±233．6、957．6±185．0，P ＜0．05，具有统计学差异；干预前后病灶周围缺血区像素亮度值分别为：351．8±146．1、573．9±162．6，P ＜0.05，具有统计学差异。结论①干预前后，脑出血病灶、病灶周围缺血区的葡萄代谢差异明显。18 F-FDG PET／CT 影像在反映病变糖代谢变化时具有优势。②脑出血病灶周围缺血区域的葡萄代谢值在干预后均得到了不同程度的恢复，但恢复程度与干预后患者恢复程度的相关性并不明确。
목적：위료관찰뇌출혈환자병조급주위구역포도당대사변화적규률，평개18 F-FDG PET／CT 재뇌출혈방면적림상응용개치。방법본연구선택경과보수간예적8명기저절구뇌출혈환자。재간예전화간예후30천분별행두부18 F-FDG PET／CT 소묘，대비분석간예전후출혈병조、병조주위결혈구포도당대사변화적정황。결과간예전후，뇌출혈병조구역적상소량도치분별위：659．8±233．6、957．6±185．0，P ＜0．05，구유통계학차이；간예전후병조주위결혈구상소량도치분별위：351．8±146．1、573．9±162．6，P ＜0.05，구유통계학차이。결론①간예전후，뇌출혈병조、병조주위결혈구적포도대사차이명현。18 F-FDG PET／CT 영상재반영병변당대사변화시구유우세。②뇌출혈병조주위결혈구역적포도대사치재간예후균득도료불동정도적회복，단회복정도여간예후환자회복정도적상관성병불명학。
Objective To analyze glucose metabolism in cerebral hemorrhage,ischemia and prognosis the value in patients wcth iottracerebral hemorrhage by PET/CT.Methods to study 8 patients with basal ganglia hemorrhage who are received twice head 18 F-FDG-PET/CT scan within 30 days.Compare the datum before treatment with after treat-ment.Results We got twice data from pre and post treatment respectively.The pixel brightness values of cerebral hem-orrhage:659.8±233.6、957.6±185.0,P <0.05;The pixel brightness values around ischemia:351.8±146.1,573.9± 162.6,P <0.05).Conclusion ①The glucose metabolism in cerebral hemorrhage and ischemia lesion is no significant difference before and after treatment.18 F-FDG-PET/CT scan has the advantage.②The glucose metabolism in ischemic area had different degree recovery,but they are no exactly relation between the recovery and after treatment were different degree of recovery,but the degree of glucose metabolism recovery and patients’.