CAJ | 학술논문

目的探讨宫颈癌根治术后患者出现阴道残端复发的相关因素。方法回顾分析173例宫颈癌根治术后患者的临床资料，包括临床分期、病理类型、阴道切缘情况、术后辅助放化疗及近距离放疗。结果术后标本阴道切缘阴性组、阳性组的平均复发时间分别为(62.29±1.89)个月、(16.75±5.63)个月，两组比较有显著性差异(<0.01)；术后无治疗组、化疗组、放疗组、同步放化疗组的平均复发时间分别为(40.18±6.18)个月、(28.02±9.07)个月、(62.91±2.34)个月、(70.97±1.49)个月，同步放化疗组较其他三组的复发曲线比较均有显著性差异(均<0.05)；术后未行近距离放疗组、行近距离放疗组平均复发时间分别为(57.53±2.59)个月、(66.62±1.60)个月，两组比较有显著性差异(<0.05)。结论宫颈癌根治术后阴道切缘阳性的患者，阴道残端复发的风险高。术后行同步放化疗可降低阴道残端复发的风险。近距离放疗能降低阴道残端复发的风险。
목적탐토궁경암근치술후환자출현음도잔단복발적상관인소。방법회고분석173례궁경암근치술후환자적림상자료，포괄림상분기、병리류형、음도절연정황、술후보조방화료급근거리방료。결과술후표본음도절연음성조、양성조적평균복발시간분별위(62.29±1.89)개월、(16.75±5.63)개월，량조비교유현저성차이(<0.01)；술후무치료조、화료조、방료조、동보방화료조적평균복발시간분별위(40.18±6.18)개월、(28.02±9.07)개월、(62.91±2.34)개월、(70.97±1.49)개월，동보방화료조교기타삼조적복발곡선비교균유현저성차이(균<0.05)；술후미행근거리방료조、행근거리방료조평균복발시간분별위(57.53±2.59)개월、(66.62±1.60)개월，량조비교유현저성차이(<0.05)。결론궁경암근치술후음도절연양성적환자，음도잔단복발적풍험고。술후행동보방화료가강저음도잔단복발적풍험。근거리방료능강저음도잔단복발적풍험。
Objective To investigate the influential factors for recur ent cervical cancer at vaginal stump fol owing radical hysterectomy.Methods This retrospective study was performed with data obtained from cases in Dalian Medical University.In total 173 cases who underwent surgical cervical cancer radical hysterectomy were studied.Results The mean time to relapse of negative and positive margin cases showed significant dif erence (62.29±1.89 months vs 16.75±5.63 months).The chemoradiotherapy after surgery group predicted to have lower risk for recur ence than others ( <0.05).The mean time to relapse of with and without brachytherapy showed statistical y significance (57.53±2.59 months vs 66.62±1.60 months).Conclusion The patients whose vaginal cut ing margin is positive have a higher recur ent risk to the negative patients.Chemoradiotherapy and rachytherapy could reduce the risk of recur ent cervical cancer of vaginal stump fol owing radical hysterectomy.