CAJ | 학술논문

目的：研究急性脑梗死患者颅内动脉狭窄或闭塞的发生率和分布特点，以及与动脉硬化危险因素之间的关系。方法根据有无颅内动脉狭窄或闭塞，将122例急性脑梗死患者分为颅内动脉狭窄或闭塞组和无颅内动脉狭窄或闭塞组。分析颅内动脉狭窄的比例和各支动脉狭窄或闭塞的比例，分析症状性颅内动脉狭窄或闭塞的比例；比较两组年龄、性别、高血压病、糖尿病、吸烟、饮酒、血脂、血同型半胱氨酸、糖化血红蛋白等危险因素的差异；分析各支动脉狭窄或闭塞与以上危险因素的关系。结果122例研究对象中，有颅内动脉狭窄或闭塞患者55例(45.1%)，其中有症状性颅内动脉狭窄或闭塞患者36/55例(65.4%)，多支动脉狭窄51/55例(92.7%)。颅内动脉狭窄或闭塞组的年龄(67.29±10.92)岁大于无颅内动脉狭窄或闭塞组(63.28±11.20)岁，差异有统计学意义(P<0.05)。大脑后动脉狭窄或闭塞患者患有糖尿病比例(58.1%)较无大脑后动脉狭窄或闭塞患者(16.7%)明显增高，差异有统计学意义(P=0.011)。结论急性脑梗死患者存在颅内动脉狭窄或闭塞的比例较高，颅内动脉狭窄或闭塞与年龄有关，大脑后动脉狭窄与糖尿病关系密切。
목적：연구급성뇌경사환자로내동맥협착혹폐새적발생솔화분포특점，이급여동맥경화위험인소지간적관계。방법근거유무로내동맥협착혹폐새，장122례급성뇌경사환자분위로내동맥협착혹폐새조화무로내동맥협착혹폐새조。분석로내동맥협착적비례화각지동맥협착혹폐새적비례，분석증상성로내동맥협착혹폐새적비례；비교량조년령、성별、고혈압병、당뇨병、흡연、음주、혈지、혈동형반광안산、당화혈홍단백등위험인소적차이；분석각지동맥협착혹폐새여이상위험인소적관계。결과122례연구대상중，유로내동맥협착혹폐새환자55례(45.1%)，기중유증상성로내동맥협착혹폐새환자36/55례(65.4%)，다지동맥협착51/55례(92.7%)。로내동맥협착혹폐새조적년령(67.29±10.92)세대우무로내동맥협착혹폐새조(63.28±11.20)세，차이유통계학의의(P<0.05)。대뇌후동맥협착혹폐새환자환유당뇨병비례(58.1%)교무대뇌후동맥협착혹폐새환자(16.7%)명현증고，차이유통계학의의(P=0.011)。결론급성뇌경사환자존재로내동맥협착혹폐새적비례교고，로내동맥협착혹폐새여년령유관，대뇌후동맥협착여당뇨병관계밀절。
Aim To study the rates and distribution of the intracranial atherosclerosis in acute cerebral infarction, and its relationship with the risk factors of the atherosclerosis. Methods 122 cases were divided into two groups depending on the intracranial stenosis or occlusion. They are intracranial stenosis or occlusion group and non-intracranial stenosis or occlusion group. The ratio of patients with intracranial stenosis or occlusion and the ratio of patients of each involved artery were studied. The ratio of patients with symptomatic intracranial stenosis or occlusion were also studied. The relationship of intracranial stenosis or occlusion with risk factors were compared, such as age, gender, hypertention, diabetes mellitus, smoke, drink, homocysteine, lipid, HbA1c. Results There were 55 patients with intracranial stenosis or occlusion in total 122 cases (45.1%), and 36 patients with symptomatic intracranial stenosis or occlusion (65.4%). There were 51 patients with multi-vessel intracranial stenosis (92.7%). The average age of the patients with intracranial stenosis or occlusion[(67.29±10.92) years] was older than that with non-intracranial stenosis or occlusion [(63.2±11.20) years], there was signiifcant difference (P<0.05). The ratio of the patients with diabetes mellitus (58.1%) in posterior cerebral artery stenosis was higher than that of the patients without diabetes mellitus (16.7%), there was statistic difference (P=0.011). Conclusion There was a high ratio of intracranial stenosis in acute cerebral infarction. There was a relationship between intracranial stenosis and age. Posterior cerebral artery stenosis was relevent to diabetes mellitus.