放射学实践
放射學實踐
방사학실천
RADIOLOGIC PRACTICE
2015年
8期
802-805
,共4页
边缘叶脑炎%副肿瘤综合征%临床特征%磁共振成像
邊緣葉腦炎%副腫瘤綜閤徵%臨床特徵%磁共振成像
변연협뇌염%부종류종합정%림상특정%자공진성상
Limbic encephalitis%Paraneoplastic syndromes%Clinical features%Magnetic resonance imaging
目的：探讨副肿瘤性边缘叶脑炎（PLE）的 MRI特征。方法：回顾性分析8例经临床诊断治疗的PLE的临床及 MRI资料。所有患者均行常规 MRI平扫及DWI检查，其中6例行增强扫描。结果：①8例病变分布均以海马及海马旁回为主，其中3例可见病变同时累及双侧杏仁核、2例累及双侧扣带回、1例累及左侧岛叶、1例累及桥脑。病变双侧对称分布7例，单侧发病1例。②信号特征：6例病变于 T1 WI 上呈较均匀稍低信号，T2 WI 呈高信号，DWI 呈稍高或等信号；2例于T1 WI呈等信号，T2 WI呈稍高信号，DWI呈等信号；所有病灶在FLAIR图像上均呈高信号。6例行增强扫描，5例病变无强化，1例可见小片状轻度强化。结论：PLE具有较典型的临床及 MRI 特征，应结合抗体检测及其它全身检查，积极寻找原发肿瘤进行综合治疗。
目的：探討副腫瘤性邊緣葉腦炎（PLE）的 MRI特徵。方法：迴顧性分析8例經臨床診斷治療的PLE的臨床及 MRI資料。所有患者均行常規 MRI平掃及DWI檢查，其中6例行增彊掃描。結果：①8例病變分佈均以海馬及海馬徬迴為主，其中3例可見病變同時纍及雙側杏仁覈、2例纍及雙側釦帶迴、1例纍及左側島葉、1例纍及橋腦。病變雙側對稱分佈7例，單側髮病1例。②信號特徵：6例病變于 T1 WI 上呈較均勻稍低信號，T2 WI 呈高信號，DWI 呈稍高或等信號；2例于T1 WI呈等信號，T2 WI呈稍高信號，DWI呈等信號；所有病竈在FLAIR圖像上均呈高信號。6例行增彊掃描，5例病變無彊化，1例可見小片狀輕度彊化。結論：PLE具有較典型的臨床及 MRI 特徵，應結閤抗體檢測及其它全身檢查，積極尋找原髮腫瘤進行綜閤治療。
목적：탐토부종류성변연협뇌염（PLE）적 MRI특정。방법：회고성분석8례경림상진단치료적PLE적림상급 MRI자료。소유환자균행상규 MRI평소급DWI검사，기중6례행증강소묘。결과：①8례병변분포균이해마급해마방회위주，기중3례가견병변동시루급쌍측행인핵、2례루급쌍측구대회、1례루급좌측도협、1례루급교뇌。병변쌍측대칭분포7례，단측발병1례。②신호특정：6례병변우 T1 WI 상정교균균초저신호，T2 WI 정고신호，DWI 정초고혹등신호；2례우T1 WI정등신호，T2 WI정초고신호，DWI정등신호；소유병조재FLAIR도상상균정고신호。6례행증강소묘，5례병변무강화，1례가견소편상경도강화。결론：PLE구유교전형적림상급 MRI 특정，응결합항체검측급기타전신검사，적겁심조원발종류진행종합치료。
Objective:To investigate the MR features of paraneoplastic limbic encephalitis (PLE).Methods:The clini-cal and MRI data of 8 cases with PLE were retrospectively analyzed.All patients underwent plain MRI and DWI scan,6 of them also underwent post-contrast MRI study.Results:①Hippocampus and parahippocampal gyrus were involved in all ca-ses,the bilateral amygdala was also involved in 3 cases,the bilateral cingulate gyri in 2 cases,the left insula in one case and the pons in one case.The lesions distributed bilateral symmetrically in 7 cases,unilateral in one case.②MRI signal changes:prolonged T1 and T2 signal,or restricted diffusion on DWI in 6 cases,isointensity on T1 WI and DWI,slight hyperintensity on FLAIR images.Six cases underwent post-contrast MRI study,only one case had mild enhancement.Conclusion:PLE had typical MRI characteristics,we should combine antibody testing and other systemic examinations,to seek the primary tumor and treat it comprehensively.
