大连医科大学学报
大連醫科大學學報
대련의과대학학보
JOURNAL OF DALIAN MEDICAL UNIVERSITY
2015年
4期
408-411
,共4页
输卵管%癌肉瘤%恶性苗勒氏管混合瘤%恶性中胚层混合瘤
輸卵管%癌肉瘤%噁性苗勒氏管混閤瘤%噁性中胚層混閤瘤
수란관%암육류%악성묘륵씨관혼합류%악성중배층혼합류
fallopian tube%carcinosarcoma%malignant mixed Müllerian tumor ( MMMT)%malignant mesodermal mixed tumor
输卵管癌肉瘤( carcinosarcomas of the fallopian tube )又称为恶性苗勒氏管混合瘤( malignant mixed Müllerian tumors, MMMTs),是一种同时含有癌和肉瘤两种组织的生殖道肿瘤,在临床上非常罕见,且侵袭性强、预后差。该病的发病机制尚未完全阐明,但单克隆起源学说支持者日益增多;其临床症状缺乏特异性,常见的症状有腹痛、不典型阴道流血及腹胀,就诊时患者常已为晚期。现尚未建立标准的治疗方案,但满意的肿瘤减灭术及以铂类为主的辅助化疗被认为有效,这需要更多研究进一步验证。
輸卵管癌肉瘤( carcinosarcomas of the fallopian tube )又稱為噁性苗勒氏管混閤瘤( malignant mixed Müllerian tumors, MMMTs),是一種同時含有癌和肉瘤兩種組織的生殖道腫瘤,在臨床上非常罕見,且侵襲性彊、預後差。該病的髮病機製尚未完全闡明,但單剋隆起源學說支持者日益增多;其臨床癥狀缺乏特異性,常見的癥狀有腹痛、不典型陰道流血及腹脹,就診時患者常已為晚期。現尚未建立標準的治療方案,但滿意的腫瘤減滅術及以鉑類為主的輔助化療被認為有效,這需要更多研究進一步驗證。
수란관암육류( carcinosarcomas of the fallopian tube )우칭위악성묘륵씨관혼합류( malignant mixed Müllerian tumors, MMMTs),시일충동시함유암화육류량충조직적생식도종류,재림상상비상한견,차침습성강、예후차。해병적발병궤제상미완전천명,단단극륭기원학설지지자일익증다;기림상증상결핍특이성,상견적증상유복통、불전형음도류혈급복창,취진시환자상이위만기。현상미건립표준적치료방안,단만의적종류감멸술급이박류위주적보조화료피인위유효,저수요경다연구진일보험증。
Carcinosarcomas of the fallopian tube ( malignant mixed Müllerian tumors, MMMTs) , composed of carcinoma-tous component and sarcomatous component, are highly aggressive, rare and biphasic tumors.Although the pathogenesis remains unclear, more and more people support the monoclonal origin theory.Most patients with carcinosarcoma of the fal-lopian tube present with nonspecific symptoms, such as abdominal pain, atypical vaginal bleeding, or abdominal disten-sion.While there are no standard therapies been established yet, optimal debulking surgery and adjuvant platinum-based combination chemotherapy are believed effective,which needs further studies to confirm.