中华麻醉学杂志
中華痳醉學雜誌
중화마취학잡지
CHINESE JOURNAL OF ANESTHESIOLOGY
2015年
4期
444-446
,共3页
张化%邸立超%吕慧敏%李莉
張化%邸立超%呂慧敏%李莉
장화%저립초%려혜민%리리
监测,生理学%脑电描记术%诱发电位,听觉%清醒镇静%二异丙酚%Narcotrend%意识指数
鑑測,生理學%腦電描記術%誘髮電位,聽覺%清醒鎮靜%二異丙酚%Narcotrend%意識指數
감측,생이학%뇌전묘기술%유발전위,은각%청성진정%이이병분%Narcotrend%의식지수
Monitoring,physiologic%Electroencephalography%Evoked potentials,auditory%Conscious sedation%Propofol%Narcotrend%Index of consciousness
目的 比较BIS、Narcotrend指数(NI)、意识指数(IoC)与听觉诱发电位指数(AAI)监测患者异丙酚镇静深度的准确性.方法 全麻下行择期手术患者60例,性别不限,年龄41 ～ 64岁,体重指数20～ 30 kg/m2,ASA分级Ⅰ或Ⅱ级.采用Marsh药代动力学参数TCI异丙酚,设定初始Ce为0.8 μg/ml,待Ce稳定后以0.1 μg/ml为梯度递增,并行OAA/S评分.TCI异丙酚前分别记录BIS值、NI值、IoC值和AAI值,此时OAA/S评分为5分,异丙酚TCI期间记录OAA/S评分依次达4分、3分、2分、1分时异丙酚Ce,采用随机数字表法确定BIS值、NI值、IoC值及AAI值的测定顺序,待数值稳定后记录5 s,取平均值.BIS值、NI值、IoC值及AAI值分别与异丙酚Ce进行Pearson相关分析.结果 BIS值、NI值、IoC值及AAI值与Ce的相关系数分别为rBIs-Ce=-0.829、rNI-Ce=-0.886、rIoC-Ce=-0.881、rAAI-Ce=-0.791 (P＜0.05).rBIS-Ce、rNI-Ce、rIoC.Ce及rAAI-Ce之间比较差异无统计学意义(P＞0.05).结论 中年患者非伤害性刺激条件下,BIS、NI、IoC及AAI监测异丙酚镇静深度的优势无差异.
目的 比較BIS、Narcotrend指數(NI)、意識指數(IoC)與聽覺誘髮電位指數(AAI)鑑測患者異丙酚鎮靜深度的準確性.方法 全痳下行擇期手術患者60例,性彆不限,年齡41 ～ 64歲,體重指數20～ 30 kg/m2,ASA分級Ⅰ或Ⅱ級.採用Marsh藥代動力學參數TCI異丙酚,設定初始Ce為0.8 μg/ml,待Ce穩定後以0.1 μg/ml為梯度遞增,併行OAA/S評分.TCI異丙酚前分彆記錄BIS值、NI值、IoC值和AAI值,此時OAA/S評分為5分,異丙酚TCI期間記錄OAA/S評分依次達4分、3分、2分、1分時異丙酚Ce,採用隨機數字錶法確定BIS值、NI值、IoC值及AAI值的測定順序,待數值穩定後記錄5 s,取平均值.BIS值、NI值、IoC值及AAI值分彆與異丙酚Ce進行Pearson相關分析.結果 BIS值、NI值、IoC值及AAI值與Ce的相關繫數分彆為rBIs-Ce=-0.829、rNI-Ce=-0.886、rIoC-Ce=-0.881、rAAI-Ce=-0.791 (P＜0.05).rBIS-Ce、rNI-Ce、rIoC.Ce及rAAI-Ce之間比較差異無統計學意義(P＞0.05).結論 中年患者非傷害性刺激條件下,BIS、NI、IoC及AAI鑑測異丙酚鎮靜深度的優勢無差異.
목적 비교BIS、Narcotrend지수(NI)、의식지수(IoC)여은각유발전위지수(AAI)감측환자이병분진정심도적준학성.방법 전마하행택기수술환자60례,성별불한,년령41 ～ 64세,체중지수20～ 30 kg/m2,ASA분급Ⅰ혹Ⅱ급.채용Marsh약대동역학삼수TCI이병분,설정초시Ce위0.8 μg/ml,대Ce은정후이0.1 μg/ml위제도체증,병행OAA/S평분.TCI이병분전분별기록BIS치、NI치、IoC치화AAI치,차시OAA/S평분위5분,이병분TCI기간기록OAA/S평분의차체4분、3분、2분、1분시이병분Ce,채용수궤수자표법학정BIS치、NI치、IoC치급AAI치적측정순서,대수치은정후기록5 s,취평균치.BIS치、NI치、IoC치급AAI치분별여이병분Ce진행Pearson상관분석.결과 BIS치、NI치、IoC치급AAI치여Ce적상관계수분별위rBIs-Ce=-0.829、rNI-Ce=-0.886、rIoC-Ce=-0.881、rAAI-Ce=-0.791 (P＜0.05).rBIS-Ce、rNI-Ce、rIoC.Ce급rAAI-Ce지간비교차이무통계학의의(P＞0.05).결론 중년환자비상해성자격조건하,BIS、NI、IoC급AAI감측이병분진정심도적우세무차이.
Objective To compare the accuracy of bispectral index (BIS),Narcotrend index (NI),index of consciousness (IoC) versus auditory evoked potential index (AAI) in monitoring the depth of sedation induced by propofol.Methods Sixty ASA physical status Ⅰ or Ⅱ patients of both sexes,aged 41-64 yr,with body mass index 20-30 kg/m2,scheduled for elective surgeries under general anesthesia,were enrolled in the study.Propofol was given by target-controlled infusion (TCI) with the initial target effect-site concentration (Ce) of 0.8 μg/ml using Marsh pharmacokinetic model,and then the Ce of propofol was increased by 0.1 μg/ml,and OAA/S was performed.Before TCI of propofol,the values of BIS,NI,IoC and AAI were recorded,and at the same time the value of OAA/S score was 5.During TCI of propofol,when OAA/S score reached 4,3,2 and 1 in turn,the Ce of propofol was recorded,the sequence for determination of the values of BIS,NI,IoC and AAI was determined using a random number table,and the values were then recorded for 5 s after the values were stable and then averaged.The parameters for vital signs were maintained within the normal range.Pearson correlation of BIS,NI,IoC and AAI values with Ce of propofol was analyzed.Results The correlation coefficients of BIS,NI,IoC and AAI values with the Ce of propofol were rBIs-Ce =-0.829,rSI-Ce =-0.886,rloC-Ce =-0.881 and rAAI-Ce =-0.791,respectively.There was no significant difference between rBIS-Ce,rNI-Ce,rIoC-Ce and rAAI-Ce.Conclusion There are no significant differences in the accuracy of BIS,NI,IoC or AAI in monitoring the depth of sedation induced by propofol in middle-aged patients with non-noxious stimuli.
