大连医科大学学报
大連醫科大學學報
대련의과대학학보
JOURNAL OF DALIAN MEDICAL UNIVERSITY
2015年
4期
388-391,394
,共5页
超声造影%肝细胞癌%病理分化
超聲造影%肝細胞癌%病理分化
초성조영%간세포암%병리분화
contrast-enhanced ultrasonography%hepatocellular carcinoma%pathological differentiation
目的：观察原发性肝细胞癌（ hepatocellular carcinoma，HCC）超声造影各时相特点，探讨不同增强模式与病理分化程度的关系。方法选择行超声造影检查诊断为HCC，且住院手术最终病理结果为HCC的患者23例作为研究对象。根据病理结果分为高分化组（10例）和中低分化组（13例）。分析其血流灌注特征，并绘制时间－强度曲线，分析造影时间－强度曲线各参数与病理分化程度的关系。结果23例肝细胞癌动脉相呈快速高增强。中低分化组92．3％（12例）门静脉相快速退出，7．7％（1例）门静脉相缓慢退出；高分化组70％（7例）门静脉相缓慢退出，30％（3例）门静脉相快速退出。两组中增强斜率、增强时间、相对峰值强度、峰值强度比值、峰值降半时间以及下降斜率比较差异有显著性意义（ P＜0．05）。结论原发性肝细胞癌造影增强表现与病理分化程度有直接关系。
目的：觀察原髮性肝細胞癌（ hepatocellular carcinoma，HCC）超聲造影各時相特點，探討不同增彊模式與病理分化程度的關繫。方法選擇行超聲造影檢查診斷為HCC，且住院手術最終病理結果為HCC的患者23例作為研究對象。根據病理結果分為高分化組（10例）和中低分化組（13例）。分析其血流灌註特徵，併繪製時間－彊度麯線，分析造影時間－彊度麯線各參數與病理分化程度的關繫。結果23例肝細胞癌動脈相呈快速高增彊。中低分化組92．3％（12例）門靜脈相快速退齣，7．7％（1例）門靜脈相緩慢退齣；高分化組70％（7例）門靜脈相緩慢退齣，30％（3例）門靜脈相快速退齣。兩組中增彊斜率、增彊時間、相對峰值彊度、峰值彊度比值、峰值降半時間以及下降斜率比較差異有顯著性意義（ P＜0．05）。結論原髮性肝細胞癌造影增彊錶現與病理分化程度有直接關繫。
목적：관찰원발성간세포암（ hepatocellular carcinoma，HCC）초성조영각시상특점，탐토불동증강모식여병리분화정도적관계。방법선택행초성조영검사진단위HCC，차주원수술최종병리결과위HCC적환자23례작위연구대상。근거병리결과분위고분화조（10례）화중저분화조（13례）。분석기혈류관주특정，병회제시간－강도곡선，분석조영시간－강도곡선각삼수여병리분화정도적관계。결과23례간세포암동맥상정쾌속고증강。중저분화조92．3％（12례）문정맥상쾌속퇴출，7．7％（1례）문정맥상완만퇴출；고분화조70％（7례）문정맥상완만퇴출，30％（3례）문정맥상쾌속퇴출。량조중증강사솔、증강시간、상대봉치강도、봉치강도비치、봉치강반시간이급하강사솔비교차이유현저성의의（ P＜0．05）。결론원발성간세포암조영증강표현여병리분화정도유직접관계。
Obej ctive To observe the appearance and characterization in every vascular phase of primary hepatocellular carcinoma ( HCC ) with contrast -enhanced ultrasonography and to evaluate whether the enhancement pattern correlates with the degree of pathological differentiation.Methods Of the patients who received contrast-enhanced ultrasonography, 23 patients with pathologically confirmed HCC were reviewed.The blood perfusion characteristics were observed.Time-intensity curve ( TIC) was drawn and the relationship was explored between the parameters of TIC and the degree of patho-logical differentiation.Results All 23 HCCs were enhanced in the arterial phase.Among them, 13 were moderately to poor-ly differentiated HCCs with 92.3%(12 lesions) quickly washed out and 7.7%(1 lesion) slowly washed out in the portal venous phase;10 were well-differentiated HCCs with 70%(7 lesions) slowly washed out and 30%(3 lesions) quickly washed out in the portal venous phase.When the two groups were compared, the parameters had significant differences (P<0.05) among contrast-enhanced slope and time, relative peak intensity, peak intensity ratio, 1/2 peak time and falling slope.Conclusions The enhanced manifestations of primary HCCs are directly related to the degree of pathological differentiation.
