CAJ | 학술논문

目的：探讨ADA、CEA水平检测对结核性和恶性胸腔积液鉴别诊断的价值。方法：检测39例结核性胸腔积液和73例恶性胸腔积液的ADA和CEA水平，比较两组ADA和CEA水平差异及诊断敏感性和特异性。结果：结核组胸腔积液ADA水平显著高于恶性组ADA水平（P<0.001），恶性组胸腔积液CEA水平显著高于结核组CEA水平（P<0.001）。ADA诊断结核性胸水的敏感性和特异性分别为89.7%(35/39)和84.9%(62/73)，CEA诊断恶性胸腔积液的敏感性和特异性分别为72.6%(53/73)和97.4%(38/39)。结论：ADA和CEA在结核性和恶性胸腔积液中的水平有显著差异，且诊断敏感性和特异性高，有助于临床鉴别诊断。
목적：탐토ADA、CEA수평검측대결핵성화악성흉강적액감별진단적개치。방법：검측39례결핵성흉강적액화73례악성흉강적액적ADA화CEA수평，비교량조ADA화CEA수평차이급진단민감성화특이성。결과：결핵조흉강적액ADA수평현저고우악성조ADA수평（P<0.001），악성조흉강적액CEA수평현저고우결핵조CEA수평（P<0.001）。ADA진단결핵성흉수적민감성화특이성분별위89.7%(35/39)화84.9%(62/73)，CEA진단악성흉강적액적민감성화특이성분별위72.6%(53/73)화97.4%(38/39)。결론：ADA화CEA재결핵성화악성흉강적액중적수평유현저차이，차진단민감성화특이성고，유조우림상감별진단。
Objective:To explore the diagnostic value of ADA and CEA in differentiation between tuberculous and malignant pleural effusion.Methods:ADA and CEA level were detected and compared in 39 tuberculous pleural effusion and 73 malignant pleural effusion patiets. The sensitivity and accuracy of ADA and CEA in tuberculous and malignant pleural effusion patients were also compared.Results: The pleural effusion ADA of tuberculous pleural effusion patients is higher than that of malignant pleural effusion patients(P<0.001).The pleural effusion CEA of malignant pleural effusion patients is higher than that of tuberculous pleural effusion patients(P<0.001).The sensitivity and accuracy of ADA in tuberculous pleural effusion patients is 89.7%(35/39) and 84.9%(62/73), The sensitivity and accuracy of CEA in malignant pleural effusion patients is 72.6%(53/73) and 97.4%(38/39). Conclusions:The pleural effusion ADA and CEA level in tuberculous and malignant pleural effusion patients is significant different,and they has high sensitivity and accuracy in these patients.The pleural effusion ADA and CEA level has great significance in differentiation between tuberculous and malignant pleural effusion.