医学检验与临床
醫學檢驗與臨床
의학검험여림상
MEDICAL LATORATORY SCIENCE AND CLINICES
2015年
3期
22-23,15
,共3页
抗心磷脂抗体%抗核抗体%抗ds-DNA%SLE
抗心燐脂抗體%抗覈抗體%抗ds-DNA%SLE
항심린지항체%항핵항체%항ds-DNA%SLE
Anticardiolipin antibody%Antinuclear antibody%Anti-ds-DNA%SLE
目的：研究探讨ANA谱﹑抗心磷脂抗体﹑抗核抗体﹑抗ds-DNA水平与SLE活动性的关系。方法：选择2013年1月至2014年6月我院风湿免疫科住院的SLE患者共125例为SLE组，同时选择同期在我院进行体检的健康者共30例为健康组。观察SLE活动期、SLE非活动期与健康组抗心磷脂抗体、抗核抗体、抗ds-DNA阳性率情况，SLE活动期、SLE非活动期与健康组抗心磷脂抗体浓度情况。结果： SLE活动期的ACA- IgG（19.21±0.79） RU/ml、ACA- IgM（17.01±0.76）RU/ml水平均显著高于健康组和SLE非活动期，差异有统计学意义（P<0.05）。健康组与SLE非活动期抗心磷脂抗体浓度相比，差异无统计学意义（P>0.05）。结论：ANA谱、抗心磷脂抗体、抗核抗体、抗ds-DNA水平的测定，对于SLE活动期的患者能够有效检测出病情，进而较好的对复发进行预测，并且有利于指导治疗。
目的：研究探討ANA譜﹑抗心燐脂抗體﹑抗覈抗體﹑抗ds-DNA水平與SLE活動性的關繫。方法：選擇2013年1月至2014年6月我院風濕免疫科住院的SLE患者共125例為SLE組，同時選擇同期在我院進行體檢的健康者共30例為健康組。觀察SLE活動期、SLE非活動期與健康組抗心燐脂抗體、抗覈抗體、抗ds-DNA暘性率情況，SLE活動期、SLE非活動期與健康組抗心燐脂抗體濃度情況。結果： SLE活動期的ACA- IgG（19.21±0.79） RU/ml、ACA- IgM（17.01±0.76）RU/ml水平均顯著高于健康組和SLE非活動期，差異有統計學意義（P<0.05）。健康組與SLE非活動期抗心燐脂抗體濃度相比，差異無統計學意義（P>0.05）。結論：ANA譜、抗心燐脂抗體、抗覈抗體、抗ds-DNA水平的測定，對于SLE活動期的患者能夠有效檢測齣病情，進而較好的對複髮進行預測，併且有利于指導治療。
목적：연구탐토ANA보﹑항심린지항체﹑항핵항체﹑항ds-DNA수평여SLE활동성적관계。방법：선택2013년1월지2014년6월아원풍습면역과주원적SLE환자공125례위SLE조，동시선택동기재아원진행체검적건강자공30례위건강조。관찰SLE활동기、SLE비활동기여건강조항심린지항체、항핵항체、항ds-DNA양성솔정황，SLE활동기、SLE비활동기여건강조항심린지항체농도정황。결과： SLE활동기적ACA- IgG（19.21±0.79） RU/ml、ACA- IgM（17.01±0.76）RU/ml수평균현저고우건강조화SLE비활동기，차이유통계학의의（P<0.05）。건강조여SLE비활동기항심린지항체농도상비，차이무통계학의의（P>0.05）。결론：ANA보、항심린지항체、항핵항체、항ds-DNA수평적측정，대우SLE활동기적환자능구유효검측출병정，진이교호적대복발진행예측，병차유리우지도치료。
Objective:To investigate ANA spectrum anti-cardiolipin antibodies, antinuclear antibody anti-ds-DNA levels and the relationship between the activity of SLE.Methods:from January 2013 to June 2014 in our hospital Rheumatology SLE patients hospitalized for a total of 125 cases of SLE group, and select the corresponding period in our hospital for examination of a total of 30 cases of healthy people healthy group. Observed active SLE, SLE and healthy inactive group of anti-cardiolipin antibodies, antinuclear antibody, anti-ds-DNA positive rate case, SLE active, SLE and healthy inactive group anticardiolipin antibody concentrations.Results: Health group and inactive SLE anti-cardiolipin antibodies, antinuclear antibodies, anti-ds-DNA positive rate, the difference was not statistically significant (P> 0.05). ACA- IgG SLE activity period (19.21 ± 0.79) RU / ml, ACA- IgM (17.01 ± 0.76) RU / ml were significantly higher than the healthy group and inactive SLE, the difference was statistically significant (P <0.05). Health group compared with inactive SLE anticardiolipin antibody concentration, the difference was not statistically significant (P> 0.05). Anti-U1-nRNP antibody of active SLE, anti-Sm antibodies.Conclusions:ANA spectrum, anti-cardiolipin antibodies, antinuclear antibodies, anti-ds-DNA levels measured for patients with active SLE can effectively detect the disease, and thus a better prediction of relapse, and help guide treatment.
