中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2015年
7期
141-144
,共4页
多指标综合评分%清热解毒口服液%正交试验%提取工艺
多指標綜閤評分%清熱解毒口服液%正交試驗%提取工藝
다지표종합평분%청열해독구복액%정교시험%제취공예
multi-index comprehensive evaluation%Qingrejiedu oral liquid%orthogonal test%extraction process
目的:优选清热解毒口服液最佳提取工艺。方法以加水量、提取时间、提取次数和含醇百分率为考察因素,每因素设计3个水平,以黄芩苷、绿原酸和栀子苷转移率及浸膏得率为指标,进行加权综合评价,用L9(34)正交表安排试验。结果清热解毒口服液最佳的提取工艺为加8倍量水提取3次,每次1h,含醇百分率为70%。结论验证试验表明通过正交试验得到的清热解毒口服液提取工艺设计合理,结果可靠,提取效果较好,具有较高的应用价值。
目的:優選清熱解毒口服液最佳提取工藝。方法以加水量、提取時間、提取次數和含醇百分率為攷察因素,每因素設計3箇水平,以黃芩苷、綠原痠和梔子苷轉移率及浸膏得率為指標,進行加權綜閤評價,用L9(34)正交錶安排試驗。結果清熱解毒口服液最佳的提取工藝為加8倍量水提取3次,每次1h,含醇百分率為70%。結論驗證試驗錶明通過正交試驗得到的清熱解毒口服液提取工藝設計閤理,結果可靠,提取效果較好,具有較高的應用價值。
목적:우선청열해독구복액최가제취공예。방법이가수량、제취시간、제취차수화함순백분솔위고찰인소,매인소설계3개수평,이황금감、록원산화치자감전이솔급침고득솔위지표,진행가권종합평개,용L9(34)정교표안배시험。결과청열해독구복액최가적제취공예위가8배량수제취3차,매차1h,함순백분솔위70%。결론험증시험표명통과정교시험득도적청열해독구복액제취공예설계합리,결과가고,제취효과교호,구유교고적응용개치。
Objective To optimize the extraction techique for Qingrejiedu oral liquid.Methods The amount of water, extraction time , extraction times and alcohol content were used as inspection factor, 3 levels per factor, with baicalin, chlorogenic acid , geniposide transfer rate and extraction rate as indexes,carries on Weighted comprehensive evaluation,the optimal extractin were screened by L9 (34 ) orthogonal test.ResuIts The optimal extraction condition of Qingrejiedu oral liquid were as follow:extraction for 3 times and 1h each time with 8-fold amount of water and 70% alcohol. ConcIusion Through the orthogonal test, the extraction process of Qingrejiedu oral liquid is designed reasonably, the result is reliable, and the extraction effect is good, and has higher application value.