中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2015年
8期
737-739
,共3页
陈勇%常艳华%郭庆%蔡颖%孙荣超
陳勇%常豔華%郭慶%蔡穎%孫榮超
진용%상염화%곽경%채영%손영초
纤维支气管镜刷片%细胞病理学%肺癌
纖維支氣管鏡刷片%細胞病理學%肺癌
섬유지기관경쇄편%세포병이학%폐암
Fiberoptic bronchoscopic brushing cells%Cytology%Lung carcinomas
目的 评估纤维支气管镜刷片细胞病理学检查在肺癌诊断及分型中的意义.方法 收集309例同时行纤维支气管镜刷片和组织活检的肺癌病例,分别计算纤维支气管镜刷片细胞病理学检查与组织学检查对肺癌检出的阳性率;以组织学活检为标准,分析纤维支气管镜刷片细胞病理学对肺癌分型判断的准确性;评价细胞病理学在肺癌诊断及分型中的意义.结果 纤维支气管镜刷片检测肺癌的阳性率与组织活检的阳性率分别为86.1％ (266/309)和83.8％ (259/309),二者联用可使诊断的阳性率提高到94.2％ (291/309);以组织学分型为标准,纤维支气管镜刷片细胞病理学诊断鳞癌、腺癌和小细胞癌的符合率较高,分别为85.1％(74/87)、82.4％(108/131)和100％(11/11);诊断其他分化差的癌符合率较低,仅12.2％(5/41).结论 纤维支气管镜刷片细胞病理学在肺癌的诊断中具有重要的应用价值,是诊断肺癌及组织分型的可靠方法,但分化差是诊断分型的一个难点.
目的 評估纖維支氣管鏡刷片細胞病理學檢查在肺癌診斷及分型中的意義.方法 收集309例同時行纖維支氣管鏡刷片和組織活檢的肺癌病例,分彆計算纖維支氣管鏡刷片細胞病理學檢查與組織學檢查對肺癌檢齣的暘性率;以組織學活檢為標準,分析纖維支氣管鏡刷片細胞病理學對肺癌分型判斷的準確性;評價細胞病理學在肺癌診斷及分型中的意義.結果 纖維支氣管鏡刷片檢測肺癌的暘性率與組織活檢的暘性率分彆為86.1％ (266/309)和83.8％ (259/309),二者聯用可使診斷的暘性率提高到94.2％ (291/309);以組織學分型為標準,纖維支氣管鏡刷片細胞病理學診斷鱗癌、腺癌和小細胞癌的符閤率較高,分彆為85.1％(74/87)、82.4％(108/131)和100％(11/11);診斷其他分化差的癌符閤率較低,僅12.2％(5/41).結論 纖維支氣管鏡刷片細胞病理學在肺癌的診斷中具有重要的應用價值,是診斷肺癌及組織分型的可靠方法,但分化差是診斷分型的一箇難點.
목적 평고섬유지기관경쇄편세포병이학검사재폐암진단급분형중적의의.방법 수집309례동시행섬유지기관경쇄편화조직활검적폐암병례,분별계산섬유지기관경쇄편세포병이학검사여조직학검사대폐암검출적양성솔;이조직학활검위표준,분석섬유지기관경쇄편세포병이학대폐암분형판단적준학성;평개세포병이학재폐암진단급분형중적의의.결과 섬유지기관경쇄편검측폐암적양성솔여조직활검적양성솔분별위86.1％ (266/309)화83.8％ (259/309),이자련용가사진단적양성솔제고도94.2％ (291/309);이조직학분형위표준,섬유지기관경쇄편세포병이학진단린암、선암화소세포암적부합솔교고,분별위85.1％(74/87)、82.4％(108/131)화100％(11/11);진단기타분화차적암부합솔교저,부12.2％(5/41).결론 섬유지기관경쇄편세포병이학재폐암적진단중구유중요적응용개치,시진단폐암급조직분형적가고방법,단분화차시진단분형적일개난점.
Objective To evaluate the significance of fiberoptic bronchoscopic brush cytology in the diagnosis and histological classification of lung carcinoma.Methods Data of 309 patients with lung carcinoma were retrospectively analyzed.Both bronchoscopic cytology and histology diagnosis were available.The positive rate of bronchoscopic cytology and tissue biopsy were calculated respectively.The classification accuracy of cytological diagnosis for lung carcinoma was evaluated.In tissue biopsy standard,evaluated the significance of bronchoscopic cytology in diagnosis and histological diagnosis.Results The positive rate of bronchoscopic cytology and tissue biopsy were 86.1％ (266/309) and 83.8％ (259/309),respectively.Bronchoscopic cytology combined with bronchial biopsy could obviously improve the positive rate to 94.2％ (291/309) in lung carcinoma diagnosis.Taking the tissue biopsy histological type as a standard,the cytotyping accuracy for brush method was 85.1％(74/87) in squamous carcinoma,82.4％(108/131) in adenocarcinoma and 100％(11/11) in small cell carcinoma for higher.However,the accuracy in diagnosing poorly differentiated carcinomas was only 12.2％ (5/ 41).Conclusion Fiberoptic bronchoscopic brush cytology plays an stable and important role in diagnosing lung carcinomas and histological type determination.However,it has limited use in diagnosing poorly differentiated carcinomas.
