CAJ | 학술논문

目的：探讨女性生殖道支原体感染检测的阳性率和药敏情况，以辅助临床合理用药。方法对2013年11月至2014年10月成都市妇女儿童中心医院门诊就诊的1530例女性生殖道分泌物进行支原体培养及体外药敏试验。依据临床信息，将其进行分组，对各组支原体检测阳性率和药敏试验结果进行分析。结果1530例女性生殖道分泌物标本的检测结果中，支原体检测结果阳性650例（42.5％）。支原体对四环素、强力霉素、交沙霉素、美满霉素及克拉霉素的敏感率较高（均高于98％），其次是罗红霉素（84.6％）；而耐药率较高的有氧氟沙星（19.2％）、阿奇霉素（18.8％）、司帕沙星（11.5％）、左氧氟沙星（4.31％）。将1530例检测结果分组，不同组群的生殖道分泌物标本支原体检测的阳性率和耐药率相比较差异有统计学意义（ P＜0.05）。结论女性生殖支原体感染检测总体阳性率较高，且在不同组群中的阳性率和耐药率有较大差异；对无明显自觉症状的育龄妇女进行孕前支原体筛查，能够更科学、更及时地指导临床治疗以及孕前和孕期保健，促进优生优育。
목적：탐토녀성생식도지원체감염검측적양성솔화약민정황，이보조림상합리용약。방법대2013년11월지2014년10월성도시부녀인동중심의원문진취진적1530례녀성생식도분비물진행지원체배양급체외약민시험。의거림상신식，장기진행분조，대각조지원체검측양성솔화약민시험결과진행분석。결과1530례녀성생식도분비물표본적검측결과중，지원체검측결과양성650례（42.5％）。지원체대사배소、강력매소、교사매소、미만매소급극랍매소적민감솔교고（균고우98％），기차시라홍매소（84.6％）；이내약솔교고적유양불사성（19.2％）、아기매소（18.8％）、사파사성（11.5％）、좌양불사성（4.31％）。장1530례검측결과분조，불동조군적생식도분비물표본지원체검측적양성솔화내약솔상비교차이유통계학의의（ P＜0.05）。결론녀성생식지원체감염검측총체양성솔교고，차재불동조군중적양성솔화내약솔유교대차이；대무명현자각증상적육령부녀진행잉전지원체사사，능구경과학、경급시지지도림상치료이급잉전화잉기보건，촉진우생우육。
Objective To investigate the positive rate of female genital tract specimens mycoplasma infection and drug susceptibility to assist clinical rational drug use.Methods Mycoplasma culture and drug susceptibility test were performed in 1 530 female outpatients in Women's and Children's Center Hospital of Chengdu City from Nov 2013 to Oct 2014.All cases were divided into different groups on the basis of clinical information, positive rate of mycoplasma infection and drug susceptibility for each group were analyzed.Results In 1 530 cases of female genital tract secretions sample test, mycoplasma infection were positive in 650 cases ( 42.5%) .Sensitive rates of mycoplasma to tetracycline, doxycycline, josamycin, mincycline and clarithromycin were high ( all above 98 %), followed by rom erythromycin (84.6 %), while ofloxacin (19.2 %), azithromycin (18.8 %), sparfloxacin (11.5 %), levofloxacin (4.31 %) were with high drug resistance rate of mycoplasma.In different groups of genital tract secretions samples, the positive rates of mycoplasma detection and the drug resistance rates had statistically differences ( P<0.05 ) .Conclusion Overall positive rate of the mycoplasma infection is high in gynecologic patients, and the positive rate and drug resistance rate differ between groups.For women of childbearing age who have no obvious self-conscious symptoms, mycoplasma screening can be more scientific, more timely to guide the clinical treatment and prenatal care which promotes eugenics.