CAJ | 학술논문

目的：研究环氧树脂类糊剂与生物陶瓷类糊剂对白细胞介素－1（IL－1）、白细胞介素－6（IL－6）、白介素－10（IL－10）、超敏C反应蛋白（ hs－CRP）影响和意义。方法从2013年4月～2015年6月收治的牙周炎患者中随机选取120例作为研究对象。随机分组法分为观察组60例，对照组60例。对观察组实施环氧树脂类糊剂进行根管填充，对照组实施生物陶瓷类糊剂进行根管填充，观察对比2组IL－1、IL－－6、IL－10、超敏C反应蛋白情况。结果治疗后2组IL－1、IL－6、hs－CRP含量显著降低，且观察组下降程度显著高于对照组（均P＜0．05）；2组IL－10水平显著升高，且观察组升高程度显著高于对照组（均P＜0．05）。观察组患者疼痛时间＜1 d占比35．00％，显著高于对照组的11．67％，且＞3 d的占比20．00％，显著低于对照组的41．67％，差异均有统计学意义（均P＜0．05）。观察组疗效为优良率98．33％，显著高于对照组的88．33％，差异有统计学意义（ P＜0．05）。观察组的PD、GI 、GCF水平显著高于对照组，差异均有统计学意义（均P＜0．05）。结论环氧树脂类糊剂作为根管填充材料，能显著改善患者IL－10、IL－6、hs－CRP等水平，缓解患者疼痛，临床效果显著。
목적：연구배양수지류호제여생물도자류호제대백세포개소－1（IL－1）、백세포개소－6（IL－6）、백개소－10（IL－10）、초민C반응단백（ hs－CRP）영향화의의。방법종2013년4월～2015년6월수치적아주염환자중수궤선취120례작위연구대상。수궤분조법분위관찰조60례，대조조60례。대관찰조실시배양수지류호제진행근관전충，대조조실시생물도자류호제진행근관전충，관찰대비2조IL－1、IL－－6、IL－10、초민C반응단백정황。결과치료후2조IL－1、IL－6、hs－CRP함량현저강저，차관찰조하강정도현저고우대조조（균P＜0．05）；2조IL－10수평현저승고，차관찰조승고정도현저고우대조조（균P＜0．05）。관찰조환자동통시간＜1 d점비35．00％，현저고우대조조적11．67％，차＞3 d적점비20．00％，현저저우대조조적41．67％，차이균유통계학의의（균P＜0．05）。관찰조료효위우량솔98．33％，현저고우대조조적88．33％，차이유통계학의의（ P＜0．05）。관찰조적PD、GI 、GCF수평현저고우대조조，차이균유통계학의의（균P＜0．05）。결론배양수지류호제작위근관전충재료，능현저개선환자IL－10、IL－6、hs－CRP등수평，완해환자동통，림상효과현저。
Objective To explore effect of the paste epoxy resins and biological ceramic paste on interleukin 1 ( IL-1 ) , interleukin 6 ( IL-6 ) , interleukin 10 (IL-10), hypersensitive c-reactive protein (hs-CRP) .Methods From April 2013 to June 2015 I branch 120 cases were randomly selected as the research object.Random grouping method divided into observation group and control group, 60 cases of control group and 60 cases of observation group.In observation group was given with epoxy resin paste for root canal filling, control group was given with biological ceramic paste for root canal filling, compared two groups of IL -1, IL-6 and IL-10, hs-CRP.ResuIts after treatment in two groups IL-1,IL-6, hs-CRP content decreased significantly, and the observation group had a significantly higher degree of decline in the control group.Two groups of IL-10 level significantly increased, higher degree was significantly higher than the control group and observation group, which were statistically significant differences ( all P<0.05 ) . Observation group of patients’ pain time<1 d accounted for 35.00% higher than that of control group was significantly higher than 11.67%.And>3 d accounted for 20.00%was lower than the control group 41.67% significantly, which were statistically significant differences (all P<0.05).Observation group’ s curative effect for instituting accounted for 98.33%, were significantly higher than that of control group 88.33%, which were statistically significant differences ( P<0.05 ) .Observation group of PD, GI, GCF level was significantly higher than the control group, which were statistically significant differences (all P<0.05).ConcIusion Epoxy resin paste such as root canal filling material, can significantly improve patients with IL-10, IL-6, hs-CRP levels, relieve patients’ pain, clinical effect is remarkable.