CAJ | 학술논문

目的分析山东省居民24h尿钠钾比与MS的关系.方法 2011年在山东省采用四阶段分层随机抽样方法抽取18～69岁居民作为研究对象,测量其血糖、血脂四项、尿钠、尿钾和尿肌酐等指标.依据24 h尿钠钾比值将研究对象按照四分位数法分组,采用二分类logistic分析钠钾比与MS的关系.结果 1 906名研究对象纳入分析,其中男性1 003人,女性903人.MS患病率为24.7％.经多因素logistic模型分析,与24 h尿钠钾比值＜4.3组相比,4.3～5.6、5.7～8.1和≥8.1组MS患病风险OR 值(95％CI)分别为1.27(0.93～ 1.71)、1.06(0.78～1.46)和1.45(1.06～1.97),趋势检验显示,P＜0.05.在MS各组分中,中心性肥胖和血压升高风险与24 h尿钠钾比之间存在线性趋势(线性趋势检验P＜0.05).结论随着24 h尿钠钾比增加,MS患病风险呈上升趋势.
목적 분석산동성거민24h뇨납갑비여MS적관계.방법 2011년재산동성채용사계단분층수궤추양방법추취18～69세거민작위연구대상,측량기혈당、혈지사항、뇨납、뇨갑화뇨기항등지표.의거24 h뇨납갑비치장연구대상안조사분위수법분조,채용이분류logistic분석납갑비여MS적관계.결과 1 906명연구대상납입분석,기중남성1 003인,녀성903인.MS환병솔위24.7％.경다인소logistic모형분석,여24 h뇨납갑비치＜4.3조상비,4.3～5.6、5.7～8.1화≥8.1조MS환병풍험OR 치(95％CI)분별위1.27(0.93～ 1.71)、1.06(0.78～1.46)화1.45(1.06～1.97),추세검험현시,P＜0.05.재MS각조분중,중심성비반화혈압승고풍험여24 h뇨납갑비지간존재선성추세(선성추세검험P＜0.05).결론 수착24 h뇨납갑비증가,MS환병풍험정상승추세.
Objective To examine the association between 24 h urinary sodium to potassium ratio and metabolic syndrome (MS) in Chinese adults.Methods A population-based cross-sectional study was conducted among Chinese adults aged 18-69 years in Shandong province in 2011.Data on 24 h urinary excretion of sodium and potassium and components of MS were examined.Participants were divided into four groups according to the quartile of 24 h urinary sodium to potassium ratio.Results Of the 1 906 Chinese adults eligible for final data analysis,471 (24.7％) were with MS.After completion of multivariate logistic regression analysis,when compared to the participants with 24 h urinary sodium to potassium ratio ＜4.3,the OR (95％CI) of participants with 24 h urinary sodium to potassium ratio during 4.3-5.6,5.7-8.1,and ≥8.1 were 1.27 (0.93-1.71),1.06 (0.78-1.46),and 1.45 (1.06-1.97),respectively (P values for linear trend ＜0.05).As for the components of MS,the odds of central obesity and elevated blood pressure but not the odds of elevated triglyeerides,low high density lipoprotein cholesterol and elevated fasting glucose,had significantly increases with successive 24 h urinary sodium to potassium ratio quartiles (P values for linear trends ＜0.05).Conclusion The 24 h urinary sodium to potassium ratio appeared significantly associated with the odds of MS.