临床药物治疗杂志
臨床藥物治療雜誌
림상약물치료잡지
CLINICAL MEDICATION JOURNAL
2015年
4期
90-92
,共3页
高血压%钙拮抗剂%硝苯地平%氟康唑%相互作用
高血壓%鈣拮抗劑%硝苯地平%氟康唑%相互作用
고혈압%개길항제%초분지평%불강서%상호작용
hypertension%calcium antagonists%nifedipine%lfuconazole%interaction
目的:探讨硝苯地平与氟康唑联用引起低血压的发生机制及处理方法,避免类似相互作用再次发生.方法:通过分析临床药师参与的1例高血压合并真菌感染患者经硝苯地平和氟康唑联合治疗后出现低血压,进行用药分析排查.结果:三唑类抗真菌药和钙离子通道阻断剂合用存在药物间的相互作用,可使钙通道拮抗剂的血药浓度升高,导致血压下降.结论:临床药师与医生组成治疗团队,能更好地保障患者的用药安全.
目的:探討硝苯地平與氟康唑聯用引起低血壓的髮生機製及處理方法,避免類似相互作用再次髮生.方法:通過分析臨床藥師參與的1例高血壓閤併真菌感染患者經硝苯地平和氟康唑聯閤治療後齣現低血壓,進行用藥分析排查.結果:三唑類抗真菌藥和鈣離子通道阻斷劑閤用存在藥物間的相互作用,可使鈣通道拮抗劑的血藥濃度升高,導緻血壓下降.結論:臨床藥師與醫生組成治療糰隊,能更好地保障患者的用藥安全.
목적:탐토초분지평여불강서련용인기저혈압적발생궤제급처리방법,피면유사상호작용재차발생.방법:통과분석림상약사삼여적1례고혈압합병진균감염환자경초분지평화불강서연합치료후출현저혈압,진행용약분석배사.결과:삼서류항진균약화개리자통도조단제합용존재약물간적상호작용,가사개통도길항제적혈약농도승고,도치혈압하강.결론:림상약사여의생조성치료단대,능경호지보장환자적용약안전.
Objective:To investigate the cause and treatment of hypotension induced by combined use of nifedipine and lfuconazole to avoid the recurrence of similar interactions.Methods:Medication analysis was conducted in one case with hypertension and fungal infection who had hypotension after combined nifedipine and lfuconazole therapy.Results: Combined use of triazole antifungal drugs and calcium channel blockers may cause drug interactions and lead to an increase in plasma concentration of calcium channel antagonists which may cause hypotension.Conclusion: The treating team composed of clinical pharmacists and doctors can better protect the safety of patient medication.
