CAJ | 학술논문

目的：在40～74岁天津市自然人群中开展大肠癌筛查，评价问卷调查、大便潜血检查（stool occult blood test，FOB）和全结肠镜检查的筛查效果，为探索大肠癌筛查策略提供参考。方法：筛查方法采用问卷调查结合FOB的两步筛查模式，经初筛确定的高危人群行全结肠镜检查明确诊断。结果：2012年5月至2014年12月，实际完成初筛2117304例，初筛顺应性39.72%；检出高危人群126118例，高危人群比例5.96%；全结肠镜检查25837例，检出腺瘤8095例，进展期腺瘤1236例、伴中重度异型增生的其他病变134例、早期癌112例、晚期癌336例，早诊率为81.52%。结论：天津市大肠癌筛查方案可以显著浓缩大肠癌高危人群，提高全结肠镜检查的阳性率，节省医疗资源。
목적：재40～74세천진시자연인군중개전대장암사사，평개문권조사、대편잠혈검사（stool occult blood test，FOB）화전결장경검사적사사효과，위탐색대장암사사책략제공삼고。방법：사사방법채용문권조사결합FOB적량보사사모식，경초사학정적고위인군행전결장경검사명학진단。결과：2012년5월지2014년12월，실제완성초사2117304례，초사순응성39.72%；검출고위인군126118례，고위인군비례5.96%；전결장경검사25837례，검출선류8095례，진전기선류1236례、반중중도이형증생적기타병변134례、조기암112례、만기암336례，조진솔위81.52%。결론：천진시대장암사사방안가이현저농축대장암고위인군，제고전결장경검사적양성솔，절성의료자원。
Objective:Colorectal cancer screening was performed on a general population with age ranging between 40 and 74 years old to evaluate the screening effects of questionnaire survey, fecal occult blood (FOB) test, and colonoscopy, as well as to provide some implications of colorectal cancer screening strategies. Methods: Two-step screening model of questionnaire survey combined with FOB test was applied for the screening. Colonoscopy was conducted in a high-risk population identified through preliminary screening as final diagnosis. Results:Based on the 2,117,304 cases screened, the screening compliance was 39.72%, and 126,118 cases (5.96%) were identified as high risk. Colonoscopies were performed on 25,837 cases, of which 8,095, 1,236, 134, 112, and 336 were identified as adenoma, advanced adenoma, severe dysplasia lesions, early cancer, and advanced cancer, respectively. The early stage di-agnostic rate was 81.52%. Conclusion:The colorectal cancer screening method performed in Tianjin can significantly concentrate on the high-risk population with colorectal cancer, increase the positivity rate of total colonoscopy, and economize medical resources.