CAJ | 학술논문

目的:探讨脑卒中患者下呼吸道感染病原菌分布特点以及药敏率以期为临床指导合理用药提供参考依据.方法:对2013年9月―2014年6月收住我院的168例脑卒中伴发下呼吸道感染患者进行细菌鉴定及药敏试验.结果:痰培养共检出菌株193株,其中革兰阴性菌118株,占61.1%,革兰阳性菌41株,占21.2%,真菌34株,占17.6%,革兰阴性菌以铜绿假单胞菌为主,对亚胺培南最敏感;革兰阳性球菌主要是金黄色葡萄球菌,对万古霉素最敏感;真菌以白色假丝酵母菌为主,对氟康唑最敏感.结论:脑卒中患者下呼吸道感染病原菌以革兰阴性菌为主,临床应及时进行细菌培养及耐药性检测,根据药敏试验结果选择抗菌药物.
목적:탐토뇌졸중환자하호흡도감염병원균분포특점이급약민솔이기위림상지도합리용약제공삼고의거.방법:대2013년9월―2014년6월수주아원적168례뇌졸중반발하호흡도감염환자진행세균감정급약민시험.결과:담배양공검출균주193주,기중혁란음성균118주,점61.1%,혁란양성균41주,점21.2%,진균34주,점17.6%,혁란음성균이동록가단포균위주,대아알배남최민감;혁란양성구균주요시금황색포도구균,대만고매소최민감;진균이백색가사효모균위주,대불강서최민감.결론:뇌졸중환자하호흡도감염병원균이혁란음성균위주,림상응급시진행세균배양급내약성검측,근거약민시험결과선택항균약물.
Objective:To evaluate distribution characteristics and drug susceptibility ratios of pathogens invovled in lower respiratory tract infection in stroke patients , in order to provide a reference for rational drug use of drugs in clinical practice.Methods:Bacterial identiifcation and testing was conducted on 168 cases of stroke patients with lower respiratory tract infection who admitted to our hospital from March 2013 to March 2014.Results: 193 strains were detected in sputum culture, among which 118 strains of Gram-negative bacilli occupying 61.1%, followed by 41 strains of Gram-positive cocci (21.2%) and 34 strains of fungi (14.3%). Among Gram-negative bacteria, the most common pathogen was Pseudomonas aeruginosa and it showed the highest sensitivity to mipenem; among Gram-positive bacteria, the most common pathogen was Staphylococcus aureus and it showed the highest sensitivity to vancomycin; among fungi, the most common pathogen was Candida albicans and it showed the highest sensitivity to lfuconazole.Conclusion:Gram-negative bacteria are the dominant pathogens in stroke patients with lower respiratory tract infection. Bacterial culture and drug resistance tests should be timely conducted in clinical practice and antibiotics should be selected according to the results of drugs susceptibility tests.