CAJ | 학술논문

目的:分析累及肺血管的多发性大动脉炎(Takayasu's arteritis,TA)的临床特点,以提高临床诊断水平.方法:回顾分析2005―2012年曾诊断为肺血栓栓塞症,因抗凝治疗效果不佳收治于北京朝阳医院呼吸与危重症医学科的TA患者的临床资料.结果:TA患者共9例,临床表现主要包括发热( 5例)、乏力( 3例)、盗汗( 2例)、头晕/晕厥(5例)、手足冷/肢体麻木(2例);呼吸系统症状主要为活动后加重的呼吸困难(8例)、咳嗽(5例)、胸痛(5例)和咯血(5例).CT肺血管检查可见病变多样,范围比较广泛,主要表现为血管狭窄、闭塞和扩张.结论:累及肺血管的TA临床表现多样,容易误诊.C T肺血管检查可以较好的反应病变特点和范围.激素和免疫抑制剂仍是治疗活动期TA的重要方法.
목적:분석루급폐혈관적다발성대동맥염(Takayasu's arteritis,TA)적림상특점,이제고림상진단수평.방법:회고분석2005―2012년증진단위폐혈전전새증,인항응치료효과불가수치우북경조양의원호흡여위중증의학과적TA환자적림상자료.결과:TA환자공9례,림상표현주요포괄발열( 5례)、핍력( 3례)、도한( 2례)、두훈/훈궐(5례)、수족랭/지체마목(2례);호흡계통증상주요위활동후가중적호흡곤난(8례)、해수(5례)、흉통(5례)화각혈(5례).CT폐혈관검사가견병변다양,범위비교엄범,주요표현위혈관협착、폐새화확장.결론:루급폐혈관적TA림상표현다양,용역오진.C T폐혈관검사가이교호적반응병변특점화범위.격소화면역억제제잉시치료활동기TA적중요방법.
Objective:To analyze the clinical characteristics and enhance the understanding of Takayasu's arteritis (TA) with pulmonary vascular involvement.Methods:The clinical data of 9 TA patients diagnosed with pulmonary thromboembolism previously, who were administrated into Beijing Chaoyang Hospital from 2005 to 2012 due to the poor efifcacy of anticoagulant therapy.Results: Totally 9 cases were included. The main clinical manifestations included fever (5 cases), fatigue (3 cases), sweating (2 cases), dizziness/syncope (5 cases), cold/numbness (2 cases); respiratory symptoms included dyspnea (8 cases), cough (5 cases), chest pain (5 cases) and hemoptysis (5 cases). CT examination showed pulmonary vascular disease mainly presenting as stenosis, occlusion and expansion.Conclusion:The clinical manifestations of TA with pulmonary vascular involvement are diverse. CT pulmonary vascular screening is a better method to relfect the characteristics and the extent of disease. Treatment should be based on activity of the disease and steroid and immunosuppressants are still the main medicine in the treatment of active TA.