CAJ | 학술논문

为探索在猪圆环病毒2型（PCV －2）阳性猪场免疫猪圆环病毒疫苗对猪场实际临床生产中猪瘟疫苗免疫效果的影响，遂将某规模化猪场的一栋存在 PCV －2感染的150头产房仔猪随机分为试验组和对照组，每组75头，试验组在14日龄免疫某进口 PCV －2杆状病毒载体灭活疫苗，对照组不免疫，并分别在PCV －2疫苗免疫前和猪瘟疫苗二免后30天每组随机采血18头仔猪检测猪瘟抗体。结果显示：PCV －2疫苗免疫前两组仔猪的猪瘟抗体水平无明显差异，猪瘟疫苗二免后30天，试验组的猪瘟抗体平均值和猪瘟抗体离散度均显著好于对照组。表明，PCV －2的感染会对猪的免疫系统造成损害从而抑制猪瘟疫苗的免疫应答，在PCV －2阳性猪场免疫猪圆环病毒疫苗能够显著增强猪瘟疫苗的免疫效果。
위탐색재저원배병독2형（PCV －2）양성저장면역저원배병독역묘대저장실제림상생산중저온역묘면역효과적영향，수장모규모화저장적일동존재 PCV －2감염적150두산방자저수궤분위시험조화대조조，매조75두，시험조재14일령면역모진구 PCV －2간상병독재체멸활역묘，대조조불면역，병분별재PCV －2역묘면역전화저온역묘이면후30천매조수궤채혈18두자저검측저온항체。결과현시：PCV －2역묘면역전량조자저적저온항체수평무명현차이，저온역묘이면후30천，시험조적저온항체평균치화저온항체리산도균현저호우대조조。표명，PCV －2적감염회대저적면역계통조성손해종이억제저온역묘적면역응답，재PCV －2양성저장면역저원배병독역묘능구현저증강저온역묘적면역효과。
In order to explore the influence of Porcine Circovirus Type 2 (PCV -2 )vaccination on the immune effect of Classical Swine Fever (CSF)vaccine in the PCV -2 positive pig farms during practical clini-cal production,150 piglets in a farrowing house of a large pig farm which had been confirmed to be PCV -2 positive were randomly divided into two groups,namely,test group and contrast group,and each 75 piglets. The piglets in the test group were immunized with the imported PCV -2 baculovirus vector inactivated vaccine when they were 14 days old.Then,18 piglets were randomly selected from each group before PCV -2 vacci-nation and 30 days after CSF revaccination respectively.The detection results showed that:there was no difference between the two groups in CSF antibody level before PCV -2 vaccination;30 days after CSF revac-cination,the average value and dispersion of CSF antibody in the test group were significantly higher than those of the contrast group.It indicated that the immune system of pigs could be damaged by PCV -2 infection and the immune response of CSF vaccine was suppressed.In addition,the immune effect of CSF vaccine could be enhanced by immunizing with PCV -2 vaccine in the PCV -2 positive pig farms.