CAJ | 학술논문

目的：探讨手术治疗对内侧颞叶癫痫认知功能的长期影响。方法选择32例内侧颞叶癫痫患者，并行前颞叶及内侧结构切除手术治疗，分别于术前、术后1月、术后半年、术后1年、术后1年半及术后2年对患者认知功能进行神经生理学评价，统计分析语言智商、操作商、记忆商和总智商的变化规律。结果内侧颞叶癫痫患者术后1月与术前比较语言智商、记忆商下降(P<0.05)，而操作商和总智商无差异(P>0.05)；术后半年语言智商、操作商和总智商与术前比较有明显改善(P<0.05)，记忆商仍下降；术后1年、术后1年半、术后2年患者的语言智商、操作商、记忆商和总智商处于一个相对稳定的水平，与术后半年比较无差异(P>0.05)。结论手术治疗能部分改善内侧颞叶癫痫患者的认知功能，手术后半年认知功能改善明显。
목적：탐토수술치료대내측섭협전간인지공능적장기영향。방법선택32례내측섭협전간환자，병행전섭협급내측결구절제수술치료，분별우술전、술후1월、술후반년、술후1년、술후1년반급술후2년대환자인지공능진행신경생이학평개，통계분석어언지상、조작상、기억상화총지상적변화규률。결과내측섭협전간환자술후1월여술전비교어언지상、기억상하강(P<0.05)，이조작상화총지상무차이(P>0.05)；술후반년어언지상、조작상화총지상여술전비교유명현개선(P<0.05)，기억상잉하강；술후1년、술후1년반、술후2년환자적어언지상、조작상、기억상화총지상처우일개상대은정적수평，여술후반년비교무차이(P>0.05)。결론수술치료능부분개선내측섭협전간환자적인지공능，수술후반년인지공능개선명현。
Objective:To investigate the postoperative cognitive function for medial temporal lobe epilepsy. Methods:32 medial temporal lobe epilepsy patients were resected away with anterior temporal lobe and the medial structures. All subjects were done with cognitive function neurophysiological evaluation on preoperative and postoperative 1 month, six months, 1 year, 1 and a half years, 2 years to analyze the change rules of language IQ, operation IQ, memory IQ and total IQ scores.Results: The language IQ and memory IQ scores of the patients for postoperative 1 month declined than those for preoperative with the medial temporal lobe epilepsy(P< 0.05), but it was not significantly different for operation IQ and total IQ scores. The language IQ, operation IQ and total IQ score for postoperative six month were significantly increased than those for preoperative (P < 0.05). However, memory IQ score declined. The language IQ, operate IQ, memory IQ and total IQ scores were at relatively stable level on postoperative 1 year, 1 and a half years, 2 years. It was not significantly different for postoperative six month (P > 0.05).Conclusion: Surgical treatment can improve part cognitive function of patients with the medial temporal lobe epilepsy. Cognitive function was significantly improved after postoperative half year.