中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2015年
26期
37-38,39
,共3页
慢性阻塞性肺疾病%血清脑钠肽%相关性研究
慢性阻塞性肺疾病%血清腦鈉肽%相關性研究
만성조새성폐질병%혈청뇌납태%상관성연구
Chronic obstructive pulmonary disease%Serum brain natriuretic peptide%Correlation research
目的：探讨和研究血清脑钠肽(BNP)水平与慢性阻塞性肺疾病(COPD)的相关性。方法80例COPD患者,对不同级别患者急性加重期、临床缓解期的BNP水平进行观察对比。结果同时期各级别COPD患者的BNP水平差异均具有统计学意义(P<0.05)；Ⅰ、Ⅱ级COPD患者急性加重期和临床缓解期的BNP水平对比差异无统计学意义(P>0.05),Ⅲ、Ⅳ级COPD患者急性加重期的BNP水平显著高于临床缓解期,差异具有统计学意义(P<0.05)。结论COPD患者疾病进展程度和BNP水平有着显著相关,病情越重则BNP水平变化越明显,可作为COPD的诊断和病情严重程度的判别依据。
目的：探討和研究血清腦鈉肽(BNP)水平與慢性阻塞性肺疾病(COPD)的相關性。方法80例COPD患者,對不同級彆患者急性加重期、臨床緩解期的BNP水平進行觀察對比。結果同時期各級彆COPD患者的BNP水平差異均具有統計學意義(P<0.05)；Ⅰ、Ⅱ級COPD患者急性加重期和臨床緩解期的BNP水平對比差異無統計學意義(P>0.05),Ⅲ、Ⅳ級COPD患者急性加重期的BNP水平顯著高于臨床緩解期,差異具有統計學意義(P<0.05)。結論COPD患者疾病進展程度和BNP水平有著顯著相關,病情越重則BNP水平變化越明顯,可作為COPD的診斷和病情嚴重程度的判彆依據。
목적：탐토화연구혈청뇌납태(BNP)수평여만성조새성폐질병(COPD)적상관성。방법80례COPD환자,대불동급별환자급성가중기、림상완해기적BNP수평진행관찰대비。결과동시기각급별COPD환자적BNP수평차이균구유통계학의의(P<0.05)；Ⅰ、Ⅱ급COPD환자급성가중기화림상완해기적BNP수평대비차이무통계학의의(P>0.05),Ⅲ、Ⅳ급COPD환자급성가중기적BNP수평현저고우림상완해기,차이구유통계학의의(P<0.05)。결론COPD환자질병진전정도화BNP수평유착현저상관,병정월중칙BNP수평변화월명현,가작위COPD적진단화병정엄중정도적판별의거。
ObjectiveTo investigate and research correlation between serum brain natriuretic peptide (BNP) level and chronic obstructive pulmonary disease (COPD).MethodsThere were 80 COPD patients. BNP levels in acute exacerbation and clinical remission were observed and compared.ResultsThere were statistically significant differences of BNP levels in different COPD degree patients at the same period (P<0.05). The difference of BNP levels had no statistical significance in grade Ⅰ and Ⅱ COPD in acute exacerbation and clinical remission patients (P>0.05). Grade Ⅲ and Ⅳ COPD in acute exacerbation had much higher BNP level than clinical remission, and the difference had statistical significance (P<0.05).ConclusionDisease progress of COPD is obviously correlated with BNP level. Obvious changes of BNP level in severe disease can be taken as reference for diagnosis and judgment.
