中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2015年
26期
29-30
,共2页
罗库溴铵%老年麻醉%拮抗
囉庫溴銨%老年痳醉%拮抗
라고추안%노년마취%길항
Rocuronium bromide%Senile anesthesia%Antagonism
目的：观察使用罗库溴铵对老年麻醉肌松时效延长而采取拮抗处理的效果。方法120例使用罗库溴铵实施肌松后出现时效延长的老年麻醉患者,随机分为观察组和对照组,每组60例。两组均采用气管插管全身麻醉,使用罗库溴铵实施肌松,手术完毕对因肌松时效延长患者,观察组使用甲硫酸新斯的明联合盐酸阿托品进行拮抗,常规监护和4个成串刺激(TOF)监测TOF从0~75%,从0~90%,从0至肌松恢复拔管即刻,从拔管即刻至残余肌松完全恢复。对照组使用生理盐水2 ml,常规监护和TOF监测TOF从0~75%,从0~90%,从0至肌松恢复拔管即刻,从拔管即刻至残余肌松完全恢复。两组患者均做好积极处理并发症准备。结果观察组能够快速拮抗肌松缩短时效,对照组肌松时效延长恢复缓慢,两组比较差异具有统计学意义(P<0.05)。结论及时合理使用甲硫酸新斯的明联合盐酸阿托品进行拮抗,可明显缩短老年麻醉肌松时效延长的恢复时间,减少术后并发症。
目的：觀察使用囉庫溴銨對老年痳醉肌鬆時效延長而採取拮抗處理的效果。方法120例使用囉庫溴銨實施肌鬆後齣現時效延長的老年痳醉患者,隨機分為觀察組和對照組,每組60例。兩組均採用氣管插管全身痳醉,使用囉庫溴銨實施肌鬆,手術完畢對因肌鬆時效延長患者,觀察組使用甲硫痠新斯的明聯閤鹽痠阿託品進行拮抗,常規鑑護和4箇成串刺激(TOF)鑑測TOF從0~75%,從0~90%,從0至肌鬆恢複拔管即刻,從拔管即刻至殘餘肌鬆完全恢複。對照組使用生理鹽水2 ml,常規鑑護和TOF鑑測TOF從0~75%,從0~90%,從0至肌鬆恢複拔管即刻,從拔管即刻至殘餘肌鬆完全恢複。兩組患者均做好積極處理併髮癥準備。結果觀察組能夠快速拮抗肌鬆縮短時效,對照組肌鬆時效延長恢複緩慢,兩組比較差異具有統計學意義(P<0.05)。結論及時閤理使用甲硫痠新斯的明聯閤鹽痠阿託品進行拮抗,可明顯縮短老年痳醉肌鬆時效延長的恢複時間,減少術後併髮癥。
목적：관찰사용라고추안대노년마취기송시효연장이채취길항처리적효과。방법120례사용라고추안실시기송후출현시효연장적노년마취환자,수궤분위관찰조화대조조,매조60례。량조균채용기관삽관전신마취,사용라고추안실시기송,수술완필대인기송시효연장환자,관찰조사용갑류산신사적명연합염산아탁품진행길항,상규감호화4개성천자격(TOF)감측TOF종0~75%,종0~90%,종0지기송회복발관즉각,종발관즉각지잔여기송완전회복。대조조사용생리염수2 ml,상규감호화TOF감측TOF종0~75%,종0~90%,종0지기송회복발관즉각,종발관즉각지잔여기송완전회복。량조환자균주호적겁처리병발증준비。결과관찰조능구쾌속길항기송축단시효,대조조기송시효연장회복완만,량조비교차이구유통계학의의(P<0.05)。결론급시합리사용갑류산신사적명연합염산아탁품진행길항,가명현축단노년마취기송시효연장적회복시간,감소술후병발증。
ObjectiveTo observe antagonism management effect of prolonged muscle relaxant time after rocuronium bromide in senile anesthesia.MethodsA total of 120 senile anesthesia patients with prolonged muscle relaxant time after rocuronium bromide were randomly divided into observation group and control group, with 60 cases in each group. Both groups received tracheal intubation general anesthesia, and rocuronium bromide for muscle relaxant. The observation group received neostigmine methylsulfate combined with atropine hydrochloride for antagonism due to prolonged muscle relaxant time after surgery. Conventional nursing and train-of-four stimulation (TOF) monitoring were taken in 0~75%, 0~90%, from 0 to extubation at recovery of muscle relaxant, and from extubation at recovery of muscle relaxant to complete recovery. The control group received 2 ml of normal saline. Conventional nursing and TOF monitoring were taken in 0~75%, 0~90%, from 0 to extubation at recovery of muscle relaxant, and from extubation at recovery of muscle relaxant to complete recovery. Both groups received active preparation for complications management.ResultsThe observation group had quick antagonism for shortening muscle relaxant time, while the control group had slow recovery time in prolonged muscle relaxant time. The difference between the two groups had statistical significance (P<0.05).ConclusionTimely implement of neostigmine methylsulfate combined with atropine hydrochloride for antagonism can obviously shorten recovery time of prolonged muscle relaxant and reduce postoperative complications.
