中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2015年
26期
9-10
,共2页
感染性休克%降钙素原%甲状腺激素%急性生理功能和慢性健康状况评分系统Ⅱ
感染性休剋%降鈣素原%甲狀腺激素%急性生理功能和慢性健康狀況評分繫統Ⅱ
감염성휴극%강개소원%갑상선격소%급성생리공능화만성건강상황평분계통Ⅱ
Septic shock%Procalcitonin%Thyroid hormones%Acute physiology andchronic health evaluationⅡ
目的：探讨感染性休克患者降钙素原(PCT)、甲状腺激素水平与急性生理功能和慢性健康状况评分系统Ⅱ(APACHEⅡ评分)的相关性。方法随机选取37例感染性休克患者，测定血清PCT、甲状腺激素水平，计算APACHEⅡ评分，进行相关性分析。结果PCT与APACHEⅡ评分呈正相关， r=0.680(P<0.05)；游离三碘甲状腺原氨酸(FT3)、游离四碘甲状腺原氨酸(FT4)与APACHEⅡ评分呈负相关， r=-0.576和-0.394(P<0.05)；总三碘甲状腺原氨酸(TT3)、总四碘甲状腺原氨酸(TT4)、促甲状腺激素(TSH)与APACHEⅡ评分不存在直线相关关系， r=-0.137、-0.258和0.092(P>0.05)。结论在感染性休克患者中， PCT、甲状腺激素中FT3、FT4水平与APACHEⅡ评分相关，一定程度上可以反映病情的严重程度。因此，在临床上，除APACHEⅡ评分外，还可以使用PCT及FT3、FT4水平来判断此类患者的病情。
目的：探討感染性休剋患者降鈣素原(PCT)、甲狀腺激素水平與急性生理功能和慢性健康狀況評分繫統Ⅱ(APACHEⅡ評分)的相關性。方法隨機選取37例感染性休剋患者，測定血清PCT、甲狀腺激素水平，計算APACHEⅡ評分，進行相關性分析。結果PCT與APACHEⅡ評分呈正相關， r=0.680(P<0.05)；遊離三碘甲狀腺原氨痠(FT3)、遊離四碘甲狀腺原氨痠(FT4)與APACHEⅡ評分呈負相關， r=-0.576和-0.394(P<0.05)；總三碘甲狀腺原氨痠(TT3)、總四碘甲狀腺原氨痠(TT4)、促甲狀腺激素(TSH)與APACHEⅡ評分不存在直線相關關繫， r=-0.137、-0.258和0.092(P>0.05)。結論在感染性休剋患者中， PCT、甲狀腺激素中FT3、FT4水平與APACHEⅡ評分相關，一定程度上可以反映病情的嚴重程度。因此，在臨床上，除APACHEⅡ評分外，還可以使用PCT及FT3、FT4水平來判斷此類患者的病情。
목적：탐토감염성휴극환자강개소원(PCT)、갑상선격소수평여급성생리공능화만성건강상황평분계통Ⅱ(APACHEⅡ평분)적상관성。방법수궤선취37례감염성휴극환자，측정혈청PCT、갑상선격소수평，계산APACHEⅡ평분，진행상관성분석。결과PCT여APACHEⅡ평분정정상관， r=0.680(P<0.05)；유리삼전갑상선원안산(FT3)、유리사전갑상선원안산(FT4)여APACHEⅡ평분정부상관， r=-0.576화-0.394(P<0.05)；총삼전갑상선원안산(TT3)、총사전갑상선원안산(TT4)、촉갑상선격소(TSH)여APACHEⅡ평분불존재직선상관관계， r=-0.137、-0.258화0.092(P>0.05)。결론재감염성휴극환자중， PCT、갑상선격소중FT3、FT4수평여APACHEⅡ평분상관，일정정도상가이반영병정적엄중정도。인차，재림상상，제APACHEⅡ평분외，환가이사용PCT급FT3、FT4수평래판단차류환자적병정。
Objective To investigate correlation in procalcitonin (PCT), thyroid hormones levels and acute physiology and chronic health evaluation Ⅱ (APACHEⅡ) scores in septic shock patients.Methods A total of 37 septic shock patients were randomly selected. Their serum PCT and thyroid hormones levels were detected, and APACHEⅡ scores were calculated. Correlation analysis was made.Results There was a positive correlation between PCT and APACHEⅡ scores,r=0.680 (P<0.05). Free triiodothyronine (FT3) and free tetraiodothyronine (FT4) were negatively correlated with APACHEⅡ scores,r=-0.576, -0.394 (P<0.05). There was no correlation in total triiodothyronine (TT3), total tetraiodothyronine (TT4), thyroid stimulating hormone (TSH) and APACHEⅡ scores,r=-0.137, -0.258, 0.092 (P>0.05).Conclusion PCT, FT3 and FT4 in thyroid hormones are correlated with APACHEⅡ scores in septic shock patients, and their correlation can show severity of the disease. In addition to APACHEⅡ scores, clinical implement of PCT, FT3 and FT4 can also provide judgment of disease status.
