CAJ | 학술논문

氧化应激在糖尿病发生发展中发挥着重要作用。胰岛素不仅能控制血糖，还能改善胰岛β细胞的功能，降低糖尿病患者氧化应激状态，尤其对于老年糖尿病患者，能延缓糖尿病并发症的发生及降低心血管事件。本文就胰岛素及其类似物对老年糖尿病患者氧化应激的影响进行综述。
양화응격재당뇨병발생발전중발휘착중요작용。이도소불부능공제혈당，환능개선이도β세포적공능，강저당뇨병환자양화응격상태，우기대우노년당뇨병환자，능연완당뇨병병발증적발생급강저심혈관사건。본문취이도소급기유사물대노년당뇨병환자양화응격적영향진행종술。
Oxidative stress plays an important role in occurrence and progression of diabetes mellitus. Insulin can not only control blood glucose, but also improve pancreatic β cell function and reduce oxidative stress in diabetes mellitus patients. Moreover, it can suspend occurrence of diabetic complications and reduce cardiovascular events in senile diabetes mellitus patients. This paper provided a summary for influence of insulin and its analogue on oxidative stress in senile diabetes mellitus patients.