CAJ | 학술논문

目的：研究多中心对比分析常规超声和MRI对胎儿畸形的诊断价值。方法对产科门诊收集的50例经常规超声诊断为胎儿畸形的孕妇进行MRI检查，以出生后随访结果及临床病理结果为标准对诊断结果进行多中心对比分析，客观评价MRI与常规超声的临床诊断价值。结果50例孕妇中胎儿畸形主要集中在胸部畸形，约为26.0%；其次为中枢神经系统畸形22.0%。两种诊断方法的准确率、特异性经统计学χ2检验，差异有统计学意义（P＜0.05）；灵敏性无无统计学意义（P＞0.05）。结论①MRI对胎儿畸形的诊断中，准确率、特异性高。②常规超声诊断中容易受干扰，但其操作简单、价格低廉，临床诊断率相对也较高，因此可作为筛查的主要手段。③笔者建议临床在对胎儿畸形的诊断中应联合两种方式进行诊断，以提高确诊率，同时可避免医疗资源的浪费。
목적：연구다중심대비분석상규초성화MRI대태인기형적진단개치。방법대산과문진수집적50례경상규초성진단위태인기형적잉부진행MRI검사，이출생후수방결과급림상병리결과위표준대진단결과진행다중심대비분석，객관평개MRI여상규초성적림상진단개치。결과50례잉부중태인기형주요집중재흉부기형，약위26.0%；기차위중추신경계통기형22.0%。량충진단방법적준학솔、특이성경통계학χ2검험，차이유통계학의의（P＜0.05）；령민성무무통계학의의（P＞0.05）。결론①MRI대태인기형적진단중，준학솔、특이성고。②상규초성진단중용역수간우，단기조작간단、개격저렴，림상진단솔상대야교고，인차가작위사사적주요수단。③필자건의림상재대태인기형적진단중응연합량충방식진행진단，이제고학진솔，동시가피면의료자원적낭비。
Objective This paper is to investigate the multi-center comparative analysis on diagnosis value of conventional ultrasound and MRI for fetal abnormalities. Methods Fifty pregnant women with fetal abnormalities admitted by the outpatient of obstetrics confirmed by conventional ultrasound diagnosis undergoing MRI examination, to follow-up results and clinical pathologic results after birth were treated as standards to conduct multi-center comparative analysis, and diagnostic value of MRI and conventional ultrasound clinical was objectively evaluated. Results The fetal abnormalities from 50 pregnant women are mainly focused chest deformity, accounting for 26.0%approximately, followed by central nervous system abnormalities at 22.0%. The diagnosis accuracy and specificity after statistics χ2 test satisfied(P<0.05) , the differences was significant, and there was not obvious difference in the sensitivity (P>0.05). Conclusion (1) MRI delivers high accuracy and specificity in the diagnosis of fetal abnormalities.(2) conventional ultrasound was susceptible to be interfered in the diagnosis, but it is featured with simple operation, low cost and relatively high clinical diagnosis rate, thus can be used as a major means for screening.(3) the authors suggest joint diagnosis of two ways should be applied in clinical diagnosis of fetal abnormalities in order to improve the diagnosis rate, and can the waste of medical resources may be avoided.