CAJ | 학술논문

目的：研究64层螺旋CT对肝癌及肝脏局灶性结节增生(FNH)的鉴别效果。方法对我院28例FNH者与24例肝癌患者为研究对象，均采取64层螺旋CT检测，扫描获得动脉期能谱系列图像及门静脉期能谱系列图像，并计算病灶-肝脏对比噪声比(CNR)、标准化碘浓度(NIC)、病灶与周围肝组织碘浓度(LNR)。结果动脉期肝癌患者CNR显著低于FNH者，比较组间比较均有统计学意义(P＜0.05)，动脉期40-50keV呈上升趋势，后随能量上升逐渐降低，而门静脉期肝癌患者40-70keV呈上升趋势，后大体为降低趋势，而FNH上升期仅为的40-50keV，50-90keV降低，后又呈增加趋势；肝癌组动脉期及门静脉期NIC、LNR显著低于FNH组，对比差异显著(P＜0.05)。结论64层螺旋CT在肝癌及肝脏局灶性结节增生鉴别中具有重要的临床意义，具有较高的临床价值。
목적：연구64층라선CT대간암급간장국조성결절증생(FNH)적감별효과。방법대아원28례FNH자여24례간암환자위연구대상，균채취64층라선CT검측，소묘획득동맥기능보계렬도상급문정맥기능보계렬도상，병계산병조-간장대비조성비(CNR)、표준화전농도(NIC)、병조여주위간조직전농도(LNR)。결과동맥기간암환자CNR현저저우FNH자，비교조간비교균유통계학의의(P＜0.05)，동맥기40-50keV정상승추세，후수능량상승축점강저，이문정맥기간암환자40-70keV정상승추세，후대체위강저추세，이FNH상승기부위적40-50keV，50-90keV강저，후우정증가추세；간암조동맥기급문정맥기NIC、LNR현저저우FNH조，대비차이현저(P＜0.05)。결론64층라선CT재간암급간장국조성결절증생감별중구유중요적림상의의，구유교고적림상개치。
Objective To study the identification effect of 64 slice spiral CT on hepatic carcinoma and hepatic focal nodular hyperplasia (FNH). Methods 28 cases of patients with FNH and 24 cases of hepatic carcinoma were taken as the research object. All of the patients received 64 slice spiral CT detection to get energy spectrum series of images in arterial phase and portal vein phase and the carrier noise ratio(CNR) between lesions and liver, normalized iodine concentration (NIC), the NIC of lesions and the surrounding tissues (LNR) of liver were calculated. Results In the arterial phase, CNR of patients with hepatic carcinoma was significantly lower than that of patients with FNH and the comparison between groups was statistically significant (P<0.05). 40-50keV showed a rising trend and then decrease with the increase of energy while in portal vein phase, 40-70keV in patients with hepatic carcinoma showed a rising trend, then showed a decreased trend and increase period of FNH leading to 40-50keV. 50-90keV decreased and then showed an increasing trend; NIC and LNR of the hepatic carcinoma (HCC) group in arterial phase and portal vein phase were significantly lower than those of FNH group and the difference was significant (P<0.05). Conclusion 64 slice spiral CT is of important clinical significance in the differentiation of hepatic carcinoma and hepatic focal nodular hyperplasia,which is of high clinical value.