中国CT和MRI杂志
中國CT和MRI雜誌
중국CT화MRI잡지
CHINESE JOURNAL OF CT AND MRI
2015年
9期
72-74,-3
,共4页
罗云辉%王艳萍%李淑明%许梅海%陈敏%刘玉涛%林丽娟%彭秀斌%任大宏
囉雲輝%王豔萍%李淑明%許梅海%陳敏%劉玉濤%林麗娟%彭秀斌%任大宏
라운휘%왕염평%리숙명%허매해%진민%류옥도%림려연%팽수빈%임대굉
早期乳腺癌%磁共振弥散加权成像%ADC值%Ki-67表达
早期乳腺癌%磁共振瀰散加權成像%ADC值%Ki-67錶達
조기유선암%자공진미산가권성상%ADC치%Ki-67표체
Early Breast Cancer%MR-DWI%ADC Value%Ki-67 Expression
目的:探讨早期乳腺癌在不同b值下的DWI成像特点及其ADC值改变、与Ki-67表达的相关性。方法对35例早期乳腺癌患者行MRI DWI检查,其b值分别取为500s/mm2、800s/mm2、1000s/mm2,分别测定癌灶在不同b值下扫描后的ADC均值,分析其DWI信号特点,比较其ADC值的差异性,并与术后病理Ki-67表达的相关性进行统计学分析。结果所有病例均为早期浸润性导管癌,瘤灶在DWI上均呈明显高信号。b值500s/mm2组(b-500组)与b值800s/mm2组(b-800组)、b-500组与b值1000s/mm2组(b-1000组)间ADC值存在统计学显著性差异(P值<0.05);而b-800组与b-1000组的ADC均值间无统计学显著性差异(P值>0.05)。b-500组、b-800组、b-1000组ADC均值分别为1.1416×10-3mm2/s、0.9258×10-3mm2/s、0.8668×10-3mm2/s。不同b值扫描后所测得瘤灶的三组ADC均值与Ki-67表达间的相关性均无统计学显著性差异(P>0.05)。结论早期乳腺癌不同b值下扫描所测得的ADC值间存在一定的差异性,选择b值为800s/mm2时扫描较为合理。当ADC值低于0.9258×10-3mm2/s时提示早期乳腺癌的可能。早期乳腺癌的ADC值与Ki-67表达之间无明显相关性。
目的:探討早期乳腺癌在不同b值下的DWI成像特點及其ADC值改變、與Ki-67錶達的相關性。方法對35例早期乳腺癌患者行MRI DWI檢查,其b值分彆取為500s/mm2、800s/mm2、1000s/mm2,分彆測定癌竈在不同b值下掃描後的ADC均值,分析其DWI信號特點,比較其ADC值的差異性,併與術後病理Ki-67錶達的相關性進行統計學分析。結果所有病例均為早期浸潤性導管癌,瘤竈在DWI上均呈明顯高信號。b值500s/mm2組(b-500組)與b值800s/mm2組(b-800組)、b-500組與b值1000s/mm2組(b-1000組)間ADC值存在統計學顯著性差異(P值<0.05);而b-800組與b-1000組的ADC均值間無統計學顯著性差異(P值>0.05)。b-500組、b-800組、b-1000組ADC均值分彆為1.1416×10-3mm2/s、0.9258×10-3mm2/s、0.8668×10-3mm2/s。不同b值掃描後所測得瘤竈的三組ADC均值與Ki-67錶達間的相關性均無統計學顯著性差異(P>0.05)。結論早期乳腺癌不同b值下掃描所測得的ADC值間存在一定的差異性,選擇b值為800s/mm2時掃描較為閤理。噹ADC值低于0.9258×10-3mm2/s時提示早期乳腺癌的可能。早期乳腺癌的ADC值與Ki-67錶達之間無明顯相關性。
목적:탐토조기유선암재불동b치하적DWI성상특점급기ADC치개변、여Ki-67표체적상관성。방법대35례조기유선암환자행MRI DWI검사,기b치분별취위500s/mm2、800s/mm2、1000s/mm2,분별측정암조재불동b치하소묘후적ADC균치,분석기DWI신호특점,비교기ADC치적차이성,병여술후병리Ki-67표체적상관성진행통계학분석。결과소유병례균위조기침윤성도관암,류조재DWI상균정명현고신호。b치500s/mm2조(b-500조)여b치800s/mm2조(b-800조)、b-500조여b치1000s/mm2조(b-1000조)간ADC치존재통계학현저성차이(P치<0.05);이b-800조여b-1000조적ADC균치간무통계학현저성차이(P치>0.05)。b-500조、b-800조、b-1000조ADC균치분별위1.1416×10-3mm2/s、0.9258×10-3mm2/s、0.8668×10-3mm2/s。불동b치소묘후소측득류조적삼조ADC균치여Ki-67표체간적상관성균무통계학현저성차이(P>0.05)。결론조기유선암불동b치하소묘소측득적ADC치간존재일정적차이성,선택b치위800s/mm2시소묘교위합리。당ADC치저우0.9258×10-3mm2/s시제시조기유선암적가능。조기유선암적ADC치여Ki-67표체지간무명현상관성。
Objective To investigate the features of MR DWI with different b values, changes of ADC value, correlation of ADC value with Ki-67 expression in early breast cancer. Methods 35 patients with early breast cancer underwent MR DWI scanning with different b values, including 500s/mm2、800s/mm2、1000s/mm2.The ADC values of the tumor lesions were measured after scanning with different b values. The DWI signal features of the tumor lesions were analyzed. The differences of the ADC Values were statistically compared, and the correlations of ADC values of the lesions with Ki-67 expressions were statistically analyzed. Results All of the patients were early breast invasive ductal carcinoma. All of the tumor lesions showed obviously high signal in DWI. There were statistically significant differences(P<0.05) between the mean values of the group of b-value 500s/mm2 (group of b-500) with group of b-value 800s/mm2 (group of b-800), Group of b-500 with group of b-value 1000s/mm2 (group of b-1000),respectively. However, there was no statistically significant difference(P>0.05) between the group of b-800 and group of b-1000.The mean ADC values were 1.1416×10-3mm2/s(group of b-500), 0.9258×10-3mm2/s (group of b-800), 0.8668×10-3mm2/s(group of b-1000),respectively. The correlations between the ADC values of the three different b-value groups and the Ki-67 expressions were not statistically different(P>0.05). Conclusion There are certain differences between the ADC values measured after DWI scanning with different b values in early breast cancer. It is more suitable to select b-value 800s/mm2 for DWI scanning in breast cancer. It is possible to diagnose early breast cancer when the ADC value is less than 0.9258×10-3mm2/s.The ADC value of early breast cancer was not obviously correlative with Ki-67 expression.