CAJ | 학술논문

目的：探讨经阴道彩色多普勒超声（TV-CDU）在针灸联合加减苍附导痰汤治疗肥胖型多囊卵巢综合征（polycystic ovary syndrome，PCOS）疗效评价中的价值。方法：选择我院临床诊断为肥胖型PCOS的患者60例，应用针灸联合加减苍附导痰汤治疗3个月，通过TV-CDU观察比较治疗前后卵巢形态学参数及卵巢基质动脉血流动力学改变情况，对卵巢形态学参数和血流动力学参数与血生化指标行统计学分析。结果：肥胖型PCOS经针灸联合加减苍附导痰汤治疗后，卵巢体积与治疗前相比明显减小、卵泡数目与治疗前相比明显减少，差异均有统计学意义（均P<0.05）；卵巢基质动脉治疗后收缩期峰值流速（peak systolic veloc-ity，PSV）（12.79±1.99）cm/s、舒张末期血流速度（peak diastolic velocity，PDV）（5.36±1.22）cm/s，与治疗前PSV（20.98±2.94）cm/s、PDV（12.02±1.77）cm/s相比明显降低，差异均有统计学意义（均P<0.05）；RI治疗后为0.55±0.08，相比治疗前0.42±0.05明显增高，差异有统计学意义（P<0.05）；促黄体生成素（LH）治疗后为（8.61±3.62）U/L，相比治疗前（14.38±8.30）U/L明显降低，差异有统计学意义（P<0.05）。结论：针灸联合加减苍附导痰汤对肥胖型PCOS有确切疗效，TV-CDU能够评价治疗前后卵巢的形态学参数及血流动力学改善状况。
목적：탐토경음도채색다보륵초성（TV-CDU）재침구연합가감창부도담탕치료비반형다낭란소종합정（polycystic ovary syndrome，PCOS）료효평개중적개치。방법：선택아원림상진단위비반형PCOS적환자60례，응용침구연합가감창부도담탕치료3개월，통과TV-CDU관찰비교치료전후란소형태학삼수급란소기질동맥혈류동역학개변정황，대란소형태학삼수화혈류동역학삼수여혈생화지표행통계학분석。결과：비반형PCOS경침구연합가감창부도담탕치료후，란소체적여치료전상비명현감소、란포수목여치료전상비명현감소，차이균유통계학의의（균P<0.05）；란소기질동맥치료후수축기봉치류속（peak systolic veloc-ity，PSV）（12.79±1.99）cm/s、서장말기혈류속도（peak diastolic velocity，PDV）（5.36±1.22）cm/s，여치료전PSV（20.98±2.94）cm/s、PDV（12.02±1.77）cm/s상비명현강저，차이균유통계학의의（균P<0.05）；RI치료후위0.55±0.08，상비치료전0.42±0.05명현증고，차이유통계학의의（P<0.05）；촉황체생성소（LH）치료후위（8.61±3.62）U/L，상비치료전（14.38±8.30）U/L명현강저，차이유통계학의의（P<0.05）。결론：침구연합가감창부도담탕대비반형PCOS유학절료효，TV-CDU능구평개치료전후란소적형태학삼수급혈류동역학개선상황。
Objective:To study the value of transvaginal colour Doppler ultrasonograpy (TV-CDU) to acupuncture combined Modified Cangfu Daotan Decoction in the treatment of fueling polycystic ovary syndrome (PCOS). Methods:Chose 60 patients clinically diagnosed with fueling PCOS,applied with acupuncture and Modified Cangfu Daotan Decoction for 3 months,compared before and after treatment by TV-CDU on ovarian form and ovarian stromal artery blood flow dynamic change. The ovarian morphology,hemodynamics parameters and blood biochemical indexes were statistically analyzed. Results:For fueling PCOS patients treated by acupuncture combined traditional Chinese medicine,the ovarian volume and the follicle number significantly decreased, the differences were statistically significant (P<0.05). After the treatment,ovarian stromal artery PSV of (12.79±1.99)cm/s,PDV of (5.36±1.22)cm/s,were significantly lower than before treatment PSV of (20.98±2.94)cm/s,PDV of (12.02±1.77)cm/s,the difference were statistically significant (P<0.05). After the treatment,RI of 0.55±0.08 was significantly higher than before treatment RI of 0.42±0.05,the difference was statistically significant (P<0.05). After the treatment,LH of (8.61±3.62)U/L was sig-nificantly lower than before treatment LH of (14.38±8.30)U/L,the difference was statistically significant (P<0.05). Conclusions:Acupuncture combined Modified Cangfu Daotan Decoction has exact therapeutic effect on fueling PCOS. TV-CDU can evaluate the treatment effect of ovarian morphology parameters and hemodynamic status.