CAJ | 학술논문

目的：探析戈舍瑞林联合比卡鲁胺片治疗前列腺癌的临床效果。方法以2014年2月～2015年2月在我院接受治疗的66例前列腺癌患者作为研究对象，将其分为对照组和观察组，每组各33例患者，其中对照组患者给予戈舍瑞林治疗，观察组患者给予戈舍瑞林联合比卡鲁胺片治疗，对比两组患者的临床疗效以及不良反应情况。结果通过治疗对照组患者的不良反应发生率为12.12%，观察组患者不良反应发生率为9.09%，比较差异无统计学意义，P>0.05；两组患者的前列腺特异性抗原值比较观察组要优于对照组，且P<0.05，差异有统计学意义。结论临床上使用戈舍瑞林联合比卡鲁胺片治疗前列腺癌是一种有效的方法，取得比较良好的治疗效果，且使用的耐药性和安全性较高。
목적：탐석과사서림연합비잡로알편치료전렬선암적림상효과。방법이2014년2월～2015년2월재아원접수치료적66례전렬선암환자작위연구대상，장기분위대조조화관찰조，매조각33례환자，기중대조조환자급여과사서림치료，관찰조환자급여과사서림연합비잡로알편치료，대비량조환자적림상료효이급불량반응정황。결과통과치료대조조환자적불량반응발생솔위12.12%，관찰조환자불량반응발생솔위9.09%，비교차이무통계학의의，P>0.05；량조환자적전렬선특이성항원치비교관찰조요우우대조조，차P<0.05，차이유통계학의의。결론림상상사용과사서림연합비잡로알편치료전렬선암시일충유효적방법，취득비교량호적치료효과，차사용적내약성화안전성교고。
Objective The clinical effect of zoladex combined casodex in treatment for prostate cancer.Methods From February 2014 to February 2015,66 cases of prostate cancer patients were as the object of study,and divided into control group and observation group,each 33 cases in each group,the control group was treated with zoladex treatment,the observation group was treated with zoladex combined casodex treatment,compared two groups of patients with clinical curative effect and adverse reaction.Results Through the treatment of the control group of patients with adverse reactions occurred rate was 12.12% observed groups of patients with adverse reaction rate was 9.09%,the difference between no statistical significance(P> 0.05), two groups of patients with prostate specific antigen value compared to the observation group was significantly better than the control group andP< 0.05, the difference was statisticaly significant.Conclusion The clinical use of zoladex combined casodex treatment of prostate cancer is a kind of effective method,has a good therapeutic effect and using the resistance and high safety.