CAJ | 학술논문

目的：对文拉法辛与氟西汀治疗抑郁症的临床疗效进行对比分析。方法选取于2012年10月～2015年5月在我院接受治疗的53例抑郁症患者，根据不同的治疗方法将患者随机分为对照组（26例）和治疗组（27例），对氟西汀和文拉法辛的临床效果进行对照研究。结果治疗组患者的治疗总有效率为92.6%，高于对照组患者的73.1%；同时治疗组患者治疗2周、4周、6周后的HAMD评分均低于对照组，差异有统计学意义（P<0.05）。结论文拉法辛治疗抑郁症的临床疗效优于氟西汀，能够使患者的临床症状得到缓解，是临床上治疗抑郁症的首选药物之一。
목적：대문랍법신여불서정치료억욱증적림상료효진행대비분석。방법선취우2012년10월～2015년5월재아원접수치료적53례억욱증환자，근거불동적치료방법장환자수궤분위대조조（26례）화치료조（27례），대불서정화문랍법신적림상효과진행대조연구。결과치료조환자적치료총유효솔위92.6%，고우대조조환자적73.1%；동시치료조환자치료2주、4주、6주후적HAMD평분균저우대조조，차이유통계학의의（P<0.05）。결논문랍법신치료억욱증적림상료효우우불서정，능구사환자적림상증상득도완해，시림상상치료억욱증적수선약물지일。
Objective Clinical effects of venlafaxine and fluoxetine in treatment of depression are to be studied.MethodsChose 53 patients of depression who were treated in hospital from October 2012 to May 2015 and separated them into control group(26 patients)and study group(27 patients)at random according to different surgery treatment,and then observed and compared clinical treatment effects of venlafaxine and fluoxetine.Results Patients’ treatment efficacy in study group was 92.6%,which was much higher than 73.1% in control group,at the same time,patients’ HAMD assessment scores after 2 weeks,four weeks and six weeks’ treatment in study group were much lower than counterparts in control group,there was a differential between two groups and such a differential had statistic value(P< 0.05).Conclusion Venlafaxine medication is much more effective in treatment of depression than fluoxetine medication,it is conducive to relieving patients’ clinical symptoms and it is one of the best choices in treatment of depression.