烟草科技
煙草科技
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TOBACCO SCIENCE & TECHNOLOGY
2015年
8期
20-24
,共5页
卢斌斌%毛健%杨陟华%曾世通%赵乐%孙世豪
盧斌斌%毛健%楊陟華%曾世通%趙樂%孫世豪
로빈빈%모건%양척화%증세통%조악%손세호
丁酸乙酯%热裂解%有害成分%Ames试验%细胞毒性试验%微核试验
丁痠乙酯%熱裂解%有害成分%Ames試驗%細胞毒性試驗%微覈試驗
정산을지%열렬해%유해성분%Ames시험%세포독성시험%미핵시험
Ethyl butyrate%Pyrolysis%Harmful component%Ames assay%Cytotoxicity assay%Micronu-cleus assay
为研究丁酸乙酯对卷烟烟气的影响,在模拟卷烟燃烧条件下对其进行热裂解实验;按照不同用量加入空白卷烟,测试主流烟气中7种有害成分(CO、HCN、NNK、B[a]P、巴豆醛、苯酚和氨)的释放量以及烟气粒相物的细菌致突变性、体外细胞毒性和体外微核率。结果表明:①丁酸乙酯在模拟卷烟燃烧温度条件下的热解行为主要是原形转移;②与空白卷烟相比,加入丁酸乙酯后7种烟气有害成分的释放量无显著增加;③3种不同剂量丁酸乙酯分别加入空白卷烟后,烟气粒相物的细菌致突变性、体外细胞毒性及体外微核测定结果均无显著增加。
為研究丁痠乙酯對捲煙煙氣的影響,在模擬捲煙燃燒條件下對其進行熱裂解實驗;按照不同用量加入空白捲煙,測試主流煙氣中7種有害成分(CO、HCN、NNK、B[a]P、巴豆醛、苯酚和氨)的釋放量以及煙氣粒相物的細菌緻突變性、體外細胞毒性和體外微覈率。結果錶明:①丁痠乙酯在模擬捲煙燃燒溫度條件下的熱解行為主要是原形轉移;②與空白捲煙相比,加入丁痠乙酯後7種煙氣有害成分的釋放量無顯著增加;③3種不同劑量丁痠乙酯分彆加入空白捲煙後,煙氣粒相物的細菌緻突變性、體外細胞毒性及體外微覈測定結果均無顯著增加。
위연구정산을지대권연연기적영향,재모의권연연소조건하대기진행열렬해실험;안조불동용량가입공백권연,측시주류연기중7충유해성분(CO、HCN、NNK、B[a]P、파두철、분분화안)적석방량이급연기립상물적세균치돌변성、체외세포독성화체외미핵솔。결과표명:①정산을지재모의권연연소온도조건하적열해행위주요시원형전이;②여공백권연상비,가입정산을지후7충연기유해성분적석방량무현저증가;③3충불동제량정산을지분별가입공백권연후,연기립상물적세균치돌변성、체외세포독성급체외미핵측정결과균무현저증가。
In order to assess the effects of ethyl butyrate addition on cigarette smoke, ethyl butyrate was pyrolyzed under conditions simulated cigarette combustion. Cigarette samples added with different rates of ethyl butyrate were prepared, and the deliveries of seven harmful components, including carbon monoxide, hydrogen cyanide, NNK, B[a]P, crotonaldehyde, phenol and ammonia, in mainstream cigarette smoke were determined, the bacterial mutagenicity, in vitro cytotoxicity and micronucleus testing of smoke particulate matter were conducted separately. The results showed that: 1) The pyrolysis behavior of ethyl butyrate mainly was intact transfer under simulated cigarette combustion conditions. 2) Comparing with the control cigarettes, the deliveries of the seven harmful components in mainstream smoke of tested cigarettes did not increase significantly. 3) The results of bacterial mutagenicity, in vitro cytotoxicity and micronucleus assays of smoke particulate matter did not change significantly after ethyl butyrate addition.